Change of signs, symptoms and voice quality evaluations throughout a 3- to 6-month empirical treatment for laryngopharyngeal reflux disease

Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
J R LechienS Saussez

Abstract

To assess the usefulness of voice quality measurements as a treatment outcome in patients with laryngopharyngeal reflux (LPR)-related symptoms. Prospective uncontrolled multi-centre study. A total of 80 clinically diagnosed LPR patients with a reflux finding score (RFS)>7 and a reflux symptom index (RSI)>13 were treated with pantoprazole and diet recommendations during 3 or 6 months, according to their evolution. RSI; RFS; blinded Grade, Roughness, Breathiness, Asthenia, Strain and Instability (GRBASI) and aerodynamic and acoustic measurements were evaluated at baseline, 3 months (n = 80), and 6 months (n = 41) post-treatment. We conducted a correlation analysis between the adherence to the diet, and the evolution of both signs and symptoms and between videolaryngostroboscopic signs and acoustic measurements. Reflux symptom index, RFS, perceptual voice quality evaluations (dysphonia, roughness, strain and instability), and aerodynamic and acoustic measurements (ie, percent jitter and percent shimmer) were significantly improved at 3 months post-treatment but not at 6 months. Percent jitter was the most useful outcome for evaluating the clinical evolution of patients throughout the treatment course. A significant relationship be...Continue Reading

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Citations

Feb 13, 2019·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jerome R LechienMichael F Vaezi
Apr 16, 2019·The Laryngoscope·Jérôme R LechienSven Saussez
Jun 10, 2019·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·A Min WangXian Ming Chen
Jun 24, 2019·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Jerome R LechienRobert T Sataloff
Feb 26, 2020·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Jerome R LechienLee M Akst
May 12, 2020·Clinical and Experimental Otorhinolaryngology·Su Il KimYoung-Gyu Eun
Jul 2, 2019·The Annals of Otology, Rhinology, and Laryngology·Jerome R LechienPetros D Karkos
Oct 19, 2019·World Journal of Clinical Cases·Jerome R LechienSven Saussez
Dec 15, 2018·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Jérôme R LechienSven Saussez
Oct 15, 2019·Ear, Nose, & Throat Journal·A Secil Kayalı DincM Melih Sahin
Jan 20, 2021·Brazilian Journal of Otorhinolaryngology·Jerome R LechienRui Imamura
Sep 21, 2018·Current Opinion in Otolaryngology & Head and Neck Surgery·Jerome R LechienPetros D Karkos
Mar 10, 2020·Gastrointestinal Endoscopy Clinics of North America·Caroline M BarrettMichael F Vaezi
Sep 29, 2019·Journal of Voice : Official Journal of the Voice Foundation·Jérôme R LechienBernard Harmegnies
Dec 2, 2020·European Annals of Otorhinolaryngology, Head and Neck Diseases·J-R LechienS Saussez
Aug 30, 2018·Folia Phoniatrica Et Logopaedica : Official Organ of the International Association of Logopedics and Phoniatrics (IALP)·Jérôme R LechienSven Saussez
Jan 16, 2022·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Nicole PizzorniAntonio Schindler

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