PMID: 26321710Sep 1, 2015Paper

Changes in Appetite, Nutrition, and Oxidative Stress Reaction of Cancer Patients during Chemotherapy

Gan to kagaku ryoho. Cancer & chemotherapy
Nao AoyamaTsuyoshi Kataoka

Abstract

Weight loss during chemotherapy is a result of malnutrition and metabolism abnormality. A few reports have focused on the treatment and prevention of weight and appetite loss in patients with advanced cancer. We evaluated the relationship between weight and appetite loss during chemotherapy by studying the meal intake of patients. In addition, we also investigated whether anorexia is associated with the level of 8-hydroxy-2' -deoxyguanosine (8-OHdG), an oxidation stress marker. The weight loss rate in patients who lack energy intake was significantly higher than that in patients with adequate energy intake. Moreover, the pre-chemotherapy total energy intake, measured according to the hospital meal consumption of patients, was lower among those with than among those without anorexia. The 8-OHdG levels in the patients with anorexia were significantly higher. In conclusion, nutritional management is important for patients even before chemotherapy is started. The 8-OHdG level can be used as an index to evaluate appetite.

Related Concepts

Related Feeds

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

Related Papers

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
Tokujiro YanoHitoshi Kohno
Current Concepts in Nutrition
A Theologides
Les Cahiers du Collège de médecine des hôpitaux de Paris
P Debray
© 2021 Meta ULC. All rights reserved