Changes in auditory nerve responses across the duration of sinusoidally amplitude-modulated electric pulse-train stimuli.

Journal of the Association for Research in Otolaryngology : JARO
Ning HuJihwan Woo

Abstract

Response rates of auditory nerve fibers (ANFs) to electric pulse trains change over time, reflecting substantial spike-rate adaptation that depends on stimulus parameters. We hypothesize that adaptation affects the representation of amplitude-modulated pulse trains used by cochlear prostheses to transmit speech information to the auditory system. We recorded cat ANF responses to sinusoidally amplitude-modulated (SAM) trains with 5,000 pulse/s carriers. Stimuli delivered by a monopolar intracochlear electrode had fixed modulation frequency (100 Hz) and depth (10%). ANF responses were assessed by spike-rate measures, while representation of modulation was evaluated by vector strength (VS) and the fundamental component of the fast Fourier transform (F(0) amplitude). These measures were assessed across the 400 ms duration of pulse-train stimuli, a duration relevant to speech stimuli. Different stimulus levels were explored and responses were categorized into four spike-rate groups to assess level effects across ANFs. The temporal pattern of rate adaptation to modulated trains was similar to that of unmodulated trains, but with less rate adaptation. VS to the modulator increased over time and tended to saturate at lower spike rates,...Continue Reading

References

Apr 1, 1992·The Journal of the Acoustical Society of America·R V Shannon
Nov 1, 1990·The Journal of the Acoustical Society of America·C J Brown, P J Abbas
Jan 1, 1987·The Annals of Otology, Rhinology, and Laryngology·D E EllisonP H Ward
Oct 1, 1972·The Annals of Otology, Rhinology, and Laryngology·N Y Kiang, E C Moxon
Sep 1, 1980·The Journal of the Acoustical Society of America·M B Sachs, E D Young
Sep 24, 1999·Hearing Research·C A MillerJ T Rubinstein
Oct 24, 2001·Journal of the Association for Research in Otolaryngology : JARO·C A MillerB K Robinson
Sep 2, 2003·Hearing Research·Donal G SinexJennifer Henderson Sabes
Nov 1, 2003·The Journal of the Acoustical Society of America·Leonid M LitvakDonald K Eddington
Nov 1, 2003·The Journal of the Acoustical Society of America·Leonid M LitvakDonald K Eddington
Jun 15, 2007·Journal of the Association for Research in Otolaryngology : JARO·Fawen ZhangNing Hu
Jan 22, 2008·Journal of the Association for Research in Otolaryngology : JARO·Charles A MillerPaul J Abbas
Mar 28, 2008·Journal of Neurophysiology·John C Middlebrooks
Jun 3, 2008·Hearing Research·Charles A MillerSiu-Ling Chi
Nov 18, 2009·Journal of Neural Engineering·Patrick L Marcus, Andrew J Fuglevand

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Citations

Nov 4, 2005·The Journal of the Acoustical Society of America·Marcia J Hay-McCutcheonPaul J Abbas
Jun 8, 2012·Journal of Neurophysiology·Joshua H GoldwynEric Shea-Brown
Dec 12, 2012·Journal of the Association for Research in Otolaryngology : JARO·Andrew T SabinBeverly A Wright
Mar 14, 2018·Journal of the Association for Research in Otolaryngology : JARO·Mahan AzadpourMario A Svirsky

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