Changes in autopsy rates among cancer patients and their impact on cancer statistics from a public health point of view: a longitudinal study from 1980 to 2010 with data from Cancer Registry Zurich

Virchows Archiv : an International Journal of Pathology
Uwe BieriSabine Rohrmann

Abstract

During the last decades, autopsy rates have dramatically decreased in many countries. The Cancer Registry Zurich, which exists since 1980, provides the opportunity to address to what extent the number of autopsies in cancer patients has changed over a longer period of time and how often autopsies provide a diagnosis of clinically undetected cancer. Data from the Cancer Registry Zurich consisting of 102,434 cancer cases among 89,933 deceased patients between 1980 and 2010 were analyzed by means of descriptive statistics. The autopsy rate declined from 60 % in 1980 to 7 % in 2010. The total number of autopsies performed decreased from 1179 in 1986 to 220 in 2010. Furthermore, there was also a decline in the rate of newly detected tumours based on autopsy information. In 1980, the rate of newly detected tumours through autopsy was 42 % compared with 2010, when the rate had declined to 17 %. A consequence of the reduced autopsy rate is the reduction of incidental findings at autopsy in cancer registration. However, this reduction has not negatively affected the total incidence of cancer. It seems that the state-of-the-art diagnostic tools used for tumour detection are sufficiently reliable, allowing the scientific community to trus...Continue Reading

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Citations

Apr 23, 2016·Langenbeck's Archives of Surgery·Kristjan UkegjiniLukas Marti
May 12, 2018·Virchows Archiv : an International Journal of Pathology·Philip EichhornTilman T Rau
Sep 25, 2018·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Courtney B ShermanNeil Mehta
Jun 16, 2017·PloS One·Britt M BlokkerJ Wolter Oosterhuis
Nov 15, 2018·Virchows Archiv : an International Journal of Pathology·Rupert LangerAlessandro Lugli
Jul 29, 2017·Der Pathologe·A-K RodewaldH Moch
May 23, 2021·Seminars in Thoracic and Cardiovascular Surgery·Anthony AloziePascal M Dohmen
Aug 24, 2021·Acta Oncologica·Anton BarchukAriana Znaor

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