Changes in body composition in heart failure patients after a resistance exercise program and branched chain amino acid supplementation

Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition
Juan Antonio Pineda-JuárezAlberto Ronquillo-Martínez

Abstract

Heart Failure (HF) is a complex syndrome, which can include the physiological, neural hormonal and metabolic complications known as "Cardiac Cachexia" (CC). In the development of CC there is a release of catabolic cytokines (Tumor Necrosis Factor-α, interleukins 1 and 6) that cause a decrease of fat free mass and fat mass. These changes in body composition might be reversed with a therapeutic combination of resistance exercise and branched chain amino acid supplementation (BCAA). Evaluate changes in body composition after a resistance exercise program and BCAA supplementation in patients with HF. In a randomized clinical trial with 3 month of follow-up anthropometric body composition analysis and stress tests were evaluated at the beginning and in the end of the study. Patients were divided into two groups; the experimental group performed the resistance exercise program and received 10 g/day BCAA supplementation, and the control group only performed the resistance exercise program. Both groups were provided with individualized diets and conventional medical treatment. Changes were found in hip circumference between the groups (p = 0.02), and muscle strength was increased in the experimental group (8%) and the control group (11...Continue Reading

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Citations

Jul 8, 2016·Journal of Cachexia, Sarcopenia and Muscle·Goran LoncarMitja Lainscak
Sep 16, 2017·European Journal of Preventive Cardiology·Louise G Shewan
Aug 31, 2019·Current Opinion in Supportive and Palliative Care·Alessia LenaMarkus S Anker
Apr 25, 2017·Nature Reviews. Cardiology·Stephan von HaehlingStefan D Anker
May 11, 2018·Geriatrics & Gerontology International·Masafumi KuzuyaHidenori Arai
Aug 4, 2020·Current Heart Failure Reports·Anastassios PhilippouMichael Koutsilieris
Jul 3, 2020·Frontiers in Physiology·J SnyderP Y Sato
Oct 30, 2020·Frontiers in Endocrinology·Danielle L KirkmanSalvatore Carbone

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