Changes in breathing, electrocortical and muscle activity in unanaesthetized fetal lambs with age

The Journal of Physiology
F ClewlowD W Walker

Abstract

Electrocortical and electro-ocular activity, breathing movements and nuchal muscle activity were recorded continuously in the unanaesthetized lamb in utero (95-135 days). Electrocortical activity was recorded simultaneously from various sites. The bi-parietal electrocorticogram gave the clearest differentiation between high- and low-voltage activity. The onset of cortical differentiation from 110 days gestation was attributed to the superimposition of high-voltage electrocortical activity at 3-10 Hz on existing low-voltage activity. Three distinct patterns in the relationships between electrocortical activity, ocular activity breathing movements and nuchal muscle activity were observed at 95-106, 107-114 and 120-135 days. Isocapnic hypoxia caused a diminution in fetal breathing from 95-135 days gestation, quantitatively greater near term. After cortical differentiation, hypoxia caused the appearance of high-voltage activity within 4 min, if low-voltage electrocortical activity was present initially. The relationship, changing with age, between electrocortical activity, breathing movements, ocular and nuchal muscle activity is discussed.

Citations

Nov 24, 2001·Brain Research. Developmental Brain Research·J L MorrisonW Riggs
Jun 9, 2005·Respiratory Physiology & Neurobiology·James E Fewell
Jun 1, 1989·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J P LipsT K Eskes
Dec 1, 1992·Pharmacology, Biochemistry, and Behavior·H H SzetoJ A Decena
Sep 1, 1991·Pharmacology, Biochemistry, and Behavior·H H SzetoY Cheng
Mar 31, 2004·Seminars in Neonatology : SN·Jalal M Abu-Shaweesh
Nov 25, 2003·Toxicology in Vitro : an International Journal Published in Association with BIBRA·J van der ValkV Baumans
Sep 9, 2005·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·H M MirghaniM Ezimokhai
Sep 11, 2010·Stress : the International Journal on the Biology of Stress·Tamara YawnoDavid W Walker
Oct 23, 1998·The Journal of Physiology·N Shinozuka, P W Nathanielsz
May 2, 2009·The Journal of Physiology·Stephen J LeeLawrence D Longo
Mar 1, 1986·American Journal of Obstetrics and Gynecology·A D Bocking, R Harding
May 15, 2013·The Journal of Steroid Biochemistry and Molecular Biology·Jonathan J HirstHannah K Palliser
Apr 12, 2011·Respiratory Physiology & Neurobiology·Jacopo P Mortola
Mar 4, 2005·Journal of Sleep Research·Mark S BlumbergEthan J Mohns
Feb 27, 2003·Journal of Sleep Research·Marcos G Frank, H Craig Heller
Feb 21, 2006·Clinical and Experimental Pharmacology & Physiology·Stuart B Hooper, Megan J Wallace
Sep 10, 2013·Experimental Physiology·Miriam E KoomeAlistair Jan Gunn
Jul 1, 1988·British Journal of Obstetrics and Gynaecology·L R Leader, P Baillie
Dec 22, 1999·American Journal of Obstetrics and Gynecology·Y KawagoeB Richardson
Apr 6, 2007·New Zealand Veterinary Journal·D J Mellor, T J Diesch
Apr 26, 2017·Nature Communications·Emily A PartridgeAlan W Flake
Aug 2, 2006·Journal of the Society for Gynecologic Investigation·Victor M PulgarJorge P Figueroa
Apr 25, 2018·The Journal of Physiology·Laura BennetRosemary S C Horne
Apr 14, 2005·PLoS Biology·Karl A E KarlssonMark S Blumberg
May 30, 2003·Journal of Perinatology : Official Journal of the California Perinatal Association·Luigi MatturriLino Rossi
May 9, 2012·Journal of the American Veterinary Medical Association·Sara C White
Apr 16, 2010·Physiological Reviews·Luc J Teppema, Albert Dahan
Mar 29, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Dan Rurak, Natalee W Bessette
Sep 3, 2020·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Christopher A LearAlistair J Gunn
May 1, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Edwin B YanDavid W Walker

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