PMID: 9554732Apr 29, 1998Paper

Changes in cardiac repolarization following short periods of ventricular pacing

Journal of Cardiovascular Electrophysiology
R GoyalF Morady

Abstract

"Cardiac memory" (primary T wave change) is thought to occur after 15 minutes to several hours of right ventricular (RV) pacing. The two components of the temporal change in repolarization are memory and accumulation. The purpose of this study was to examine quantitatively the effect of short periods of ventricular pacing on the human cardiac action potential, using monophasic action potential (MAP) recordings. Thirty-one patients (ages 43+/-14 years) with structurally normal hearts undergoing a clinically indicated electrophysiologic procedure were enrolled. Catheters were placed in the right atrium (RA) and RV, and a MAP catheter was positioned at the RV septum. APD90 was calculated from digitized MAP recordings. MAP morphology comparisons were performed using the root mean square (RMS) of the difference between complexes. All pacing was at 500-msec cycle length. There were four pacing protocols: (1) RA pacing was performed for approximately 15 minutes to evaluate temporal stability of the MAP recordings (5 pts); (2) to evaluate the memory phenomenon, four successive 1-minute episodes of RV pacing were interspersed with 2 minutes of RA pacing (5 pts); (3) the accumulation phenomenon was evaluated by assessing the effects of 1...Continue Reading

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Citations

Oct 3, 2002·The Journal of Emergency Medicine·James C Kolb
Feb 27, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Kun-Tai LeeWen-Ter Lai
Feb 16, 2012·Circulation Journal : Official Journal of the Japanese Circulation Society·Kyoung-Min ParkYou-Ho Kim
Nov 15, 2005·The Journal of Physiology·Michael R Rosen, Ira S Cohen
Mar 27, 2009·The Kaohsiung Journal of Medical Sciences·Kun-Tai LeeWen-Ter Lai
Feb 27, 2007·International Journal of Cardiology·Kun-Tai LeeWen-Ter Lai
Aug 31, 2006·Cardiology Clinics·S Serge BaroldAnne B Curtis
Aug 22, 2006·Journal of Electrocardiology·S Serge Barold, Bengt Herweg
Dec 20, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kornelis W PatbergMichael R Rosen
May 6, 2014·Journal of Electrocardiology·Antoine Ayer, Christian Juhl Terkelsen
Jul 13, 2016·Herzschrittmachertherapie & Elektrophysiologie·B HerwegS S Barold
May 14, 2003·Journal of Cardiovascular Electrophysiology·Imad Libbus, David S Rosenbaum
Jan 13, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Imad LibbusDavid S Rosenbaum
Dec 22, 1999·Pacing and Clinical Electrophysiology : PACE·J J Goldberger, A H Kadish

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