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Changes in cellular prion protein expression, processing and localisation during differentiation of the neuronal cell line CAD 5

Biology of the Cell

Nov 17, 2019

Zuzana FremuntovaKarel Holada

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Abstract

Cellular prion protein (PrPC ) is infamous for its role in prion diseases. The physiological function of PrPC remains enigmatic, but several studies point to its involvement in cell differentiation processes. To test this possibility, we monitored PrPC changes during the differentiation...read more

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Biological Markers
Cell Differentiation Process
Plasma Membrane
Coronary Arteriosclerosis
Lipids
Neurons
PrPC Proteins
Neurites
Cell Line, Tumor
Prion Diseases
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Changes in cellular prion protein expression, processing and localisation during differentiation of the neuronal cell line CAD 5

Biology of the Cell

Nov 17, 2019

Zuzana FremuntovaKarel Holada

PMID: 31736091

DOI: 10.1111/boc.201900045

Abstract

Cellular prion protein (PrPC ) is infamous for its role in prion diseases. The physiological function of PrPC remains enigmatic, but several studies point to its involvement in cell differentiation processes. To test this possibility, we monitored PrPC changes during the differentiation...read more

Mentioned in this Paper

Biological Markers
Cell Differentiation Process
Plasma Membrane
Coronary Arteriosclerosis
Lipids

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