Abstract
Impaired cerebral oxygenation, which is reflected by measuring jugular bulb oxygenation, is thought to play an important role in the development of neurological injury after cardiac operations with cardiopulmonary bypass (CPB). The effects of cardiopulmonary temperature and blood gas strategy on cerebral oxygenation are not fully appreciated. Sixty patients were randomly allocated into four equal groups (cold alpha-stat, cold pH-stat, warm alpha-stat and warm pH-stat) to compare the effect of these perfusion strategies on cerebral oxygenation monitored by jugular bulb oximetry [jugular bulb oxygen saturation (SjO(2)) and arterial-jugular bulb oxygen content difference (AjDO(2))]. Jugular bulb oxygen saturation and AjDO(2) were measured before CPB, after 5, 20, 40 min on CPB, at start and end of rewarming, 5 min before the end of CPB and 10 min after CPB. Two-way analysis of variance was used to model the lowest SjO(2) and highest AjDO(2) during CPB, with CPB temperature and blood gas management as contributing factors. Significant changes in SjO(2) were only related to the type of blood gas management, with no significant difference between warm and cold CPB patients. In addition, during rewarming, desaturation (SjO(2) </= 50%)...Continue Reading
References
May 1, 1992·Anesthesia and Analgesia·T NakajimaO Takaki
May 1, 1992·The Annals of Thoracic Surgery·N D CroughwellJ G Reves
Aug 1, 1990·Stroke; a Journal of Cerebral Circulation·D S ProughC Taylor
Dec 1, 1989·The Annals of Thoracic Surgery·P JohnssonE Ståhl
Jan 1, 1982·Anesthesiology·A K ReamG Silverberg
Feb 1, 1995·Anesthesiology·J G StoneD B Shrebnick
Dec 1, 1994·The Annals of Thoracic Surgery·N D CroughwellB J Leone
Jan 1, 1993·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·R L PatelG E Venn
Mar 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·R PretreB Faidutti
Jan 1, 1997·Anesthesia and Analgesia·T GotoH Uozumi
Jan 1, 1997·Critical Care Clinics·Z Feldman, C S Robertson
Apr 1, 1997·Anesthesiology·B F Matta, A M Lam
Jun 1, 1997·Journal of Clinical Anesthesia·H P GrocottJ G Reves
Jul 1, 1997·The Journal of Thoracic and Cardiovascular Surgery·G PlourdeA Ptito
Oct 23, 1997·Critical Care Medicine·K J SapireB Chance
Jul 17, 1998·Anesthesiology·F HänelJ Schulte am Esch
Jul 27, 1999·The Annals of Thoracic Surgery·Y KadoiN Fujita
Feb 16, 2000·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·N OkanoF Goto
Aug 17, 2000·Intensive Care Medicine·B ViguéB Bissonnette
Feb 13, 2001·Anaesthesia·M Shaaban AliI Latto
Mar 29, 2001·European Journal of Anaesthesiology·M Shaaban-AliI P Latto
Jul 27, 2001·Acta Anaesthesiologica Scandinavica·Y KadoiN Fujita
Mar 21, 2002·Acta Anaesthesiologica Scandinavica·M Shaaban-AliE G Butchart
Apr 18, 2002·Perfusion·R Ian JohnsonBrian M Fabri
Dec 23, 2003·Anaesthesia·M Shaaban AliF Kirkham
Citations
May 7, 2010·The Neurologist·Yolanda Carrascal, Angel L Guerrero
Aug 31, 2013·Journal of Clinical Monitoring and Computing·Steven TeerenstraPatrick W Weerwind
May 18, 2010·Journal of Cardiothoracic and Vascular Anesthesia·Marina SvyatetsJean Charchaflieh
Mar 16, 2005·Anaesthesia·M Shaaban AliF Kirkham
Oct 17, 2006·Paediatric Anaesthesia·Nobuo Jimi, Tsunehiko Shin
Jul 30, 2011·PloS One·Michael G BuhnerkempeColleen T Webb
Sep 9, 2006·Seminars in Cardiothoracic and Vascular Anesthesia·George N Djaiani
Dec 2, 2006·Journal of Cardiothoracic and Vascular Anesthesia·Anis BarakaMohamad El-Khatib
Aug 4, 2006·Journal of Cardiothoracic and Vascular Anesthesia·Francois J SmithPieter J Becker
Dec 22, 2017·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·Eric D CaineKristen Quinlan
Nov 3, 2007·Acta Anaesthesiologica Scandinavica·E Kottenberg-AssenmacherJ Peters
Aug 4, 2006·Journal of Cardiothoracic and Vascular Anesthesia·George M Hoffman
Jun 28, 2011·Resuscitation·G Curley, J G Laffey