Abstract
We evaluate changes in choroidal thickness after intravitreal injection (IVI) therapy for pachychoroid neovasculopathy (PNV). An observational, retrospective, consecutive case series was studied of 18 patients (18 eyes) who underwent anti-vascular endothelial growth factor (VEGF) therapy for PNV. The 18 fellow eyes in these patients were used as controls. All eyes were evaluated with swept-source optical coherence tomography (SS-OCT) and optical coherence tomography angiography (OCTA). Mean patient age was 68.3 ± 7.0 years. Mean follow-up was 16.4 ± 2.0 months. No differences in the best-corrected visual acuity (BCVA) of the affected eyes were observed between baseline and 12-month follow-up (median Early Treatment of Diabetic Retinopathy Study [ETDRS] score, 77.5 vs. 76 letters, P = 0.074; median logMAR, 0.22 vs. 0.22, P = 0.453). However, subfoveal choroidal thickness (SFCT) decreased significantly from a mean of 317.7 ± 39.9 μm at baseline to 266.9 ± 56.3 μm at 12 months (P ≤ 0.001). Median change in SFCT at 12 months was 44.0 μm (range, 17-133 μm). SFCT decreased by 16% from baseline to month 12. The change in SFCT at 12 months was highly correlated with the number of IVI (rs = 0.762, P ≤ 0.001). No significant changes in S...Continue Reading
Citations
Mar 27, 2019·Current Eye Research·Sibel InanUmit Ubeyt Inan
Apr 24, 2019·Cutaneous and Ocular Toxicology·Mehmet Cem SabanerReşat Duman
Jan 5, 2020·Current Eye Research·Gokhan DemirKorhan Fazıl
Jul 4, 2019·Eye·Riccardo SacconiGiuseppe Querques
Oct 31, 2019·The British Journal of Ophthalmology·Raimondo ForteEric H Souied
Feb 16, 2019·Scientific Reports·Byung Ju JungWon Ki Lee
Apr 23, 2020·Japanese Journal of Ophthalmology·Yasuo Yanagi
Sep 25, 2019·Indian Journal of Ophthalmology·Rupak RoySugandha Goel
Sep 19, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Magdalena KalJerzy Mackiewicz
Nov 2, 2019·Scientific Reports·Chee Wai WongChui Ming Gemmy Cheung
Jul 31, 2020·International Ophthalmology·Francesco SartiniChiara Posarelli
Oct 14, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Marco PellegriniGiuseppe Giannaccare
Jan 9, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Young Ho KimJaeryung Oh
Jan 12, 2021·PloS One·Yong-Yeon SongMin-Woo Lee
Feb 11, 2021·Eye·Taiichi HikichiMoe Yamauchi
Feb 20, 2021·Scientific Reports·Geun Woo LeeKyung Jun Choi
Apr 27, 2021·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·Alaa Din AbdinBerthold Seitz
Apr 23, 2021·Clinical Ophthalmology·Sufian ElfandiAkitaka Tsujikawa
Jun 12, 2021·Current Eye Research·Rui HuaMeixia Zhang
Jul 2, 2021·BMC Ophthalmology·Benedikt SchwormJakob Siedlecki
Jul 31, 2021·European Journal of Ophthalmology·Pradeep SagarShorya Vardhan Azad