Changes in colonization of residents and staff of a long-term care facility and an adjacent acute-care hospital geriatric unit by multidrug-resistant bacteria over a four-year period

Scandinavian Journal of Infectious Diseases
Albert MarchNeil Woodford

Abstract

In 2012 we undertook a screening study for Enterobacteriaceae with extended-spectrum β-lactamases (ESBLs), derepressed or acquired high-level AmpC cephalosporinases, and metallo-β-lactamases (MBLs), and also methicillin-resistant Staphylococcus aureus (MRSA), in a long-term care facility (LTCF1) and the associated acute care hospital geriatric ward in Bolzano, northern Italy. The study followed up an initial survey carried out in LTCF1 in 2008. For comparison, screening in 2012 was extended to a second LTCF. Urine samples and rectal, inguinal, oropharyngeal, and nasal swabs were plated on selective agars. Isolates were typed by pulsed-field gel electrophoresis. Resistance genes and Escherichia coli belonging to ST131 were sought by PCR. Demographic data were collected. Fewer residents of LTCF1 were colonized with multidrug-resistant (MDR) bacteria in 2012: all MDR organisms, 53.8% vs 74.8% in 2008; ESBL producers, 49.0% vs 64.0% in 2008; MRSA, 13.2% vs 38.7% in 2008; only 2 MBL-producers were isolated in 2012 vs 8 in 2008. Colonization of staff in LTCF1 by MDR bacteria had also decreased (overall 10.5% in 2012 vs 27.5% in 2008). Changed case mixes and risk factors, together with strengthened hygiene measures probably underlie t...Continue Reading

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Citations

Dec 20, 2015·Virulence·Dafna YahavMical Paul
Jul 18, 2015·American Journal of Infection Control·Mounia N Hocine, Laura Temime
Apr 17, 2017·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M GiufrèM Cerquetti
Mar 13, 2018·Antimicrobial Resistance and Infection Control·Elisabetta NucleoUNKNOWN ESCMID Study Group Elderly Infections – ESGIE
Sep 6, 2019·Aging Clinical and Experimental Research·Yaara Leibovici-WeissmanDafna Yahav
Jul 15, 2020·Antimicrobial Resistance and Infection Control·Richard AschbacherUNKNOWN GLISTer (Gruppo di Lavoro per lo Studio delle Infezioni nelle Residenze Sanitarie Assistite e Strutture Assimilabili) workin
Jun 7, 2019·International Journal of Environmental Research and Public Health·Claudia PetersAnja Schablon
Mar 12, 2021·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Marine de LarocheAurélien Dinh

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