Changes in concentrations of fluoroquinolones and of ciprofloxacin-resistant Enterobacteriaceae in chicken feces and manure stored in a heap

Journal of Environmental Quality
Ramona MoraruPatrick Dabert

Abstract

This study evaluated the impact of storing chicken manure on the degradation of enrofloxacin (ENR) and ciprofloxacin (CIP), and on the survival of CIP-resistant Enterobacteriaceae. At 24 d of age, half of 8900 chickens received ENR for 5 d. After the animals departed, their manure was stored in two heaps for 63 d. Enterobacteriaceae were cultured on media containing 0 to 32 mg L⁻¹ of CIP. A total of 320 isolates were fingerprinted using enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) to evaluate community structure. Initial concentrations of ENR and CIP in the heap were 22 and 1.8 mg kg⁻¹, respectively. Seventy-three percent of the two fluoroquinolones were eliminated during storage. The administration of ENR led to a 5.1 log₋₁₀ decrease in Enterobacteriaceae concentrations and emergence of CIP-resistant bacteria, which became dominant in the feces. concentrations decreased 1.2 to 2.3 log₋₁₀ 2 d after the heaps were made and continued to decline during storage. No resistant were found by Day 63. The highest CIP minimum inhibitory concentration (MIC) values observed among isolates of and of both and sp. were 128 and 4 mg L⁻¹, respectively. The dominant ERIC-PCR profiles changed over time. The...Continue Reading

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Citations

Jan 19, 2016·Frontiers in Veterinary Science·KaNa SangZongHui Yuan
Jul 5, 2015·Environmental Science and Pollution Research International·Xuewen LiJinfeng Wang
Apr 16, 2014·Journal of Veterinary Pharmacology and Therapeutics·M SlanaM Sollner-Dolenc
Jan 1, 2013·Environmental Toxicology and Pharmacology·Marko Slana, Marija Sollner Dolenc
Oct 29, 2015·Environmental Science and Pollution Research International·Marko Slana, Marija Sollner-Dolenc
Apr 13, 2017·Environmental Science and Pollution Research International·M SlanaM Sollner-Dolenc

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