Dec 5, 1975

Changes in erythrocyte 2,3 diphosphoglycerate in women following short term maximal exercise

European Journal of Applied Physiology and Occupational Physiology
H W BonnerC K Buffington

Abstract

15 untrained women were subjected to a walking treadmill test to determine the influence of maximal exercise upon synthesis of erythrocyte 2,3 DPG. Although there was a 9.8% increase in the 2,3 DPG content following exercise, there was a concomitant 9.4% increase in the hemoglobin level; therefore, when 2,3 DPG is expressed as a ratio to hemoglobin (See Article), there was no significant change as a result of exercise stress. It was suggested that three additive factors produced during strenuous exercise; decreased pH; increased hemoglobin concentration; and increased CO2 production result in by-product inhibition of 2,3 DPG synthesis. It is concluded that 2,3 DPG does not provide a physiologic benefit in the adaptation of the oxygen transport system to exercise.

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Citations

Mentioned in this Paper

Dioxygen
Treadmill Test
Diphosphoglyceric Acids
Hemoglobin Measurement
Eryhem
Metabolic Inhibition
Dipstick Assessment of Hemoglobin Concentration
Oxygen Consumption
Oxygen Transport
Carbon Dioxide

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