Changes in eye movement parameters in the presence of an artificial central scotoma.

Restorative Neurology and Neuroscience
Paul LénéAarlenne Zein Khan

Abstract

Central vision loss, such as in the case of age-related macular degeneration (AMD), has a a major negative impact on patients' quality of life. However, some patients have shown spontaneous adaptive strategies development, mostly relying on their peripheral vision. This study assesses eye movement and eccentric visual function adaptive behaviors of a healthy population in the presence of simulated central vision loss. We wished to determine how central vision loss affects eye movements, specifically the foveal-target alignment. Fifteen healthy participants (7 females, M = 21.69, SD = 2.13) discriminated the orientation of a Gabor relative to the vertical located at 12 deg of eccentricity to the right of fixation, in the presence of a gaze-contingent artificial central scotoma either visible or invisible. The artificial central scotoma was 4° diameter in order to simulate an earlier stage of degenerative disease while still impairing foveal vision. The target's orientation varied between 10° counter-clockwise and 10° clockwise. Each participant performed four blocks of 75 trials each per day over 10 days, the first day being a baseline without scotoma. We found changes in the endpoints of the 1st saccade over the practice days. ...Continue Reading

References

Jan 1, 1979·Experimental Brain Research·J Rovamo, V Virsu
Jan 1, 1978·Vision Research·C PrablancJ F Echallier
Jan 1, 1976·Vision Research·P E Hallett, A D Lightstone
Mar 12, 1992·Nature·C D Gilbert, T N Wiesel
Feb 1, 1992·Vision Research·S J Heinen, A A Skavenski
Jan 1, 1991·Vision Research·S G WhittakerL R Swieson
Jan 1, 1991·Experimental Brain Research·S J Heinen, A A Skavenski
Jan 1, 1990·Perception·G K Edgar, A T Smith
Jan 1, 1989·Vision Research·B J Kröse, B Julesz
Jan 1, 1986·Vision Research·Z Kapoula, D A Robinson
Jan 1, 1986·Biological cybernetics·B Fischer, L Rogal
Jan 1, 1974·Journal of the Optical Society of America·M Millodot, A Lamont
Jun 1, 1981·Annals of Neurology·O MeienbergL Stark
Feb 1, 1980·The Quarterly Journal of Experimental Psychology·M I Posner
Jan 1, 1980·Vision Research·J P RijsdijkG J van der Wildt
Dec 1, 1993·Vision Research·P D Spear
Jan 1, 1993·Experimental Brain Research·C J Erkelens, J Hulleman
Sep 1, 1995·Canadian Journal of Physiology and Pharmacology·Y M Chino
Jan 1, 1997·Vision Research·M Carrasco, K S Frieder
Apr 1, 1997·Ophthalmology·D C Fletcher, R A Schuchard
Nov 18, 1998·Journal of Neurophysiology·J Wallman, A F Fuchs
Jan 6, 1999·Optometry and Vision Science : Official Publication of the American Academy of Optometry·U L NilssonS E Nilsson
Nov 2, 2001·Cognitive Psychology·J Intriligator, P Cavanagh
Dec 5, 2002·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Michael D Crossland, Gary S Rubin
Feb 5, 2003·Behavior Research Methods, Instruments, & Computers : a Journal of the Psychonomic Society, Inc·Eyal M Reingold, Lester C Loschky
Feb 5, 2003·Behavior Research Methods, Instruments, & Computers : a Journal of the Psychonomic Society, Inc·Frans W CornelissenJohn Palmer
Sep 11, 2004·Vision Research·Michael VarsoriAndrew R Whatham
Jun 7, 2005·Visual Neuroscience·Sing-Hang Cheung, Gordon E Legge

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Nippon Ganka Gakkai zasshi
T Imanishi
Klinische Monatsblätter für Augenheilkunde
U COMBERG, P LOMMATZSCH
Bulletin de la Société belge d'ophtalmologie
H Minh-Tri, P Betz
Transactions of the Ophthalmological Society of New Zealand
G POWELL
© 2021 Meta ULC. All rights reserved