Changes in food intake and circulating leptin due to gastrointestinal parasitism in lambs of two breeds

Journal of Animal Science
Konstantinos ZaralisI Kyriazakis

Abstract

A reduction in food intake is a prominent feature of many infectious diseases. However, the underlying mechanisms of parasite-induced anorexia in sheep are poorly understood. Here, we tested the hypotheses (a) that the degree of parasite-induced anorexia in lambs is influenced by their growth potential and (b) that nematode infection results in elevated plasma leptin concentration in lambs. The hypotheses were tested with Suffolk x Greyface (S) and Scottish Black-face (B) lambs that are known to differ in their growth potential (S lambs are of greater growth potential than B lambs). During a primary parasite infection, 24 out of 48 lambs per breed were trickle-infected with 7,000 infective Teladorsagia circumcincta larvae per day, 3 d/wk, for a period of 12 wk (experiment I). The lambs were then dewormed, and after a 2-wk interval, half of the 24 lambs per breed that were previously infected were reinfected for another 12 wk with the same parasite and dose as used in the primary infection (experiment II). In both experiments, infected lambs were fed grass pellets for ad libitum intake, whereas noninfected lambs were fed grass pellets for either ad libitum or restricted intakes. The S lambs were more susceptible than B lambs to ...Continue Reading

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Citations

Nov 1, 2010·Animal : an International Journal of Animal Bioscience·J L SartinR R Wilborn
Mar 24, 2012·Animal : an International Journal of Animal Bioscience·A R G Wylie
Mar 24, 2012·Animal : an International Journal of Animal Bioscience·A B Doeschl-Wilson
Sep 24, 2011·Integrative and Comparative Biology·Susannah S FrenchGregory E Demas
May 23, 2017·International Journal for Parasitology·J G M HoudijkM R Hutchings

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