PMID: 11317080Apr 24, 2001Paper

Changes in HIV-1 incidence in heroin users in Guangxi Province, China

Journal of Acquired Immune Deficiency Syndromes : JAIDS
S LaiX F Yu

Abstract

Guangxi Province, China recently experienced an outbreak of HIV-1 infection among heroin users. We studied HIV-1 incidence rates and associated risk factors for HIV-1 infection among heroin users residing in Pingxiang City. A total of 318 heroin users were followed from February 1998 through January 1999 (median follow-up: 8.1 months). Of these, 130 were prospectively followed from January through September 1999 (median follow-up: 8.3 months). HIV-1 and hepatitis C virus (HCV) incidence rates for each period were calculated. A generalized estimating equation approach was implemented to identify independent risk factors associated with HIV-1 infection across both periods. Among 318 study participants, 97.2% were men. The median age was 22 years. Approximately 60% reported sharing needles. HIV-1 prevalence at baseline was 15.4%. During the first follow-up period, HIV-1 incidence was 2.38 per 100 person years (py), and HCV incidence was 26.8 per 100 py. During the second follow-up period, HIV-1 incidence was 6.86 per 100 py, and HCV incidence was 28.9 per 100 py. After controlling for age and other factors, HCV seropositivity, history of sexually transmitted diseases, and sharing needles were independently associated with HIV-1 in...Continue Reading

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Citations

Dec 3, 2005·AIDS and Behavior·Xiushi YangHuasong Luo
Dec 16, 2005·Cell Research·Tian Xin Chu, Judith A Levy
Nov 3, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Rebecca J GartenXiao-Fang Yu
Aug 17, 2004·AIDS Patient Care and STDs·Wei-Ti ChenWilliam L Holzemer
May 3, 2006·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Theodore M HammettDon C Des Jarlais
Sep 15, 2007·The International Journal on Drug Policy·Holly HaganPeter L Flom
Dec 19, 2006·Drug and Alcohol Dependence·Roberta ScheinmannShiela Strauss
Sep 14, 2006·Addiction·Wei LiuJ Brooks Jackson
Mar 28, 2008·Tropical Medicine & International Health : TM & IH·Li ZhangYiming Shao
Feb 27, 2007·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Yuanzhi ZhangYiming Shao
Mar 10, 2007·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·Liu WeiJ Brooks Jackson
May 27, 2004·World Journal of Gastroenterology : WJG·Yu-Hua RuanYi-Ming Shao
Sep 19, 2017·The Cochrane Database of Systematic Reviews·Lucy PlattMatthew Hickman
Feb 6, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Xiaoxu HanHong Shang
Oct 16, 2004·Expert Review of Anti-infective Therapy·Mark W Tyndall

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