Changes in human knee ligament stiffness secondary to osteoarthritis

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Zair FishkinIsrael Ziv

Abstract

Stiffness of the medial (MCL) and lateral (LCL) collateral ligaments was compared between a group of 10 patients undergoing total knee arthroplasty for varus degenerative osteoarthritis (OAP), a group of 10 osteoarthritic cadaveric knees (OAC), and a group of 10 non-osteoarthritic cadaveric knees (NOA). A load-elongation curve was obtained for the medial and lateral compartments of each knee using an instrumented Moreland spreader. A strain gage (SG) was attached to the spreader handle and strain was calibrated to load applied against the spread distance. In extension, medial compartment stiffness of the OAP, OAC, and NOA groups was 60.7+/-16, 52.8+/-9.3 and 21.4+/-5.0 N/mm, respectively. Lateral compartment stiffness in extension was 29.2+/-9.2, 33.3+/-10.3 and 19.5+/-5.3 N/mm, for OAP, OAC, and NOA, respectively. Differences in stiffness between the OAP and OAC groups were not statistically significant (p > 0.05). However, the osteoarthritic groups (OAP and OAC) demonstrated a statistically significantly (p < 0.05) increase in ligament stiffness when compared to the NOA group. Following knee arthroplasty, stiffer medial structures in extension may lead to flexion contracture and accelerated polyethylene wear. Adequate bone re...Continue Reading

References

Feb 1, 1977·The Journal of Bone and Joint Surgery. British Volume·M A FreemanR C Todd
Jan 1, 1976·Clinical Orthopaedics and Related Research·J H BargrenR C Todd
Jun 1, 1976·Clinical Orthopaedics and Related Research·P S TrentB Wolf
Apr 1, 1986·Clinical Orthopaedics and Related Research·T M Wright, D L Bartel
Jan 1, 1986·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·S L WooW H Akeson
Nov 1, 1973·Journal of Biomechanics·C J Wang, P S Walker
Aug 1, 1980·Acta Orthopaedica Scandinavica·K KolstadA Wigren
Jul 1, 1993·Journal of Biomedical Engineering·A SambatakakisG Newton
Jun 1, 1996·British Journal of Rheumatology·M WadaS Shimada
Aug 16, 1997·Lancet·P Creamer, M C Hochberg
Feb 10, 1998·The American Journal of Medicine·N E Lane, J M Thompson
Jan 1, 2000·The Journal of Bone and Joint Surgery. British Volume·S A Ibrahim
Feb 2, 2000·The Journal of Arthroplasty·L F Draganich, L A Pottenger
Sep 17, 2014·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Woo-Shin ChoJaeyoun Yoon

❮ Previous
Next ❯

Citations

Jun 16, 2009·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·K M GhoshAndrew A Amis
Nov 27, 2010·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Joseph M HartMark D Miller
Oct 17, 2007·International Orthopaedics·Yoshinori IshiiShin-Ichi Toyabe
Jun 16, 2011·International Orthopaedics·Georg MatziolisCarsten Perka
Sep 28, 2012·Current Reviews in Musculoskeletal Medicine·Evan M Schwechter, Wolfgang Fitz
Feb 20, 2004·The Journal of Arthroplasty·Paul ZalzalMitchell J Winemaker
Jul 13, 2011·Journal of Biomechanical Engineering·Dawie J van den HeeverEdwin Dillon
Dec 30, 2006·The Journal of Orthopaedic and Sports Physical Therapy·Carol A OatisSandra K Lennon
Jun 24, 2014·Journal of Athletic Training·Patricia AronsonChristopher D Ingersoll
Feb 27, 2014·The Journal of Orthopaedic and Sports Physical Therapy·Alden L TaylorNorman W Gill
Jun 10, 2015·Computer Methods in Biomechanics and Biomedical Engineering·Simone BersiniCarlo A Frigo
Jun 15, 2010·The Knee·Andreas C SchirmMarkus S Kuster
Apr 25, 2009·Journal of Biomechanics·Emily J MillerKenton R Kaufman
Sep 14, 2014·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Donald W HohmanWofgang Fitz
Mar 11, 2010·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Kanishka M GhoshAndrew A Amis
Jun 9, 2009·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Satoshi HamaiScott A Banks
Mar 2, 2010·Arthritis Care & Research·Sharon J DixonKay M Crossley
Feb 11, 2015·The Journal of Arthroplasty·Hideki Mizu-UchiDarryl D D'Lima
Jan 11, 2005·Osteoarthritis and Cartilage·Alfons S K de HoogeWim B van den Berg
Feb 13, 2009·The Knee·Markus S KusterRochelle L Nicholls
Dec 1, 2018·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Joshua D RothMaury L Hull
Nov 12, 2019·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Yoshinori IshiiShin-Ichi Toyabe
Feb 26, 2020·The Journal of the American Academy of Orthopaedic Surgeons·Amy CheungKwong Yuen Chiu
Dec 19, 2012·Clinical Orthopaedics and Related Research·Shigetoshi OkamotoYukihide Iwamoto
Jun 17, 2020·Expert Review of Molecular Diagnostics·Paula Casal-BeiroaJoana Magalhães
Sep 3, 2020·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Shizuka SasakiYasuyuki Ishibashi
Jan 25, 2020·Annals of Biomedical Engineering·S H Hosseini NasabW R Taylor
Mar 8, 2017·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Sae Kwang KwonKwan Kyu Park
Jul 6, 2017·Archives of Orthopaedic and Trauma Surgery·Laura C SlaneLennart Scheys
Nov 21, 2007·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·M SwankS Bignozzi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Orthopaedic and Sports Physical Therapy
Karrie L Hamstra-WrightKathleen A Swanik
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Azhar M MericanAndrew Amis
Australasian Physical & Engineering Sciences in Medicine
Dawie van den HeeverEdwin Dillon
© 2022 Meta ULC. All rights reserved