Changes in intestinal microbiota across an altitudinal gradient in the lizard Phrynocephalus vlangalii

Ecology and Evolution
Wenya ZhangWei Zhao

Abstract

High altitude is an important driving force in animal evolution. However, the effect of altitude on gut microbial communities in reptiles has not been examined in detail. Here, we investigated the intestinal microbiota of three populations of the lizard Phrynocephalus vlangalii living at different altitudes using 16S rRNA gene sequencing. Bacteroidetes, Firmicutes, and Proteobacteria were the most abundant phyla. Bacteroides, Odoribacter, and Parabacteroides were the most abundant genera. Significant differences in the intestinal microbiota composition were found among the three populations from different altitudes. The proportions of Verrucomicrobia and Akkermansia decreased, whereas Bacteroides increased significantly with altitude. Greater abundance of Bacteroides at higher altitude led to the fractional increase in the phylum Bacteroides relative to other phyla. Hypoxia may be the main factor that caused intestinal microbiota variation in P. vlangalii along the altitude gradient. Overall, our study suggested that the community composition and structure of intestinal microbiota of the lizard P. vlangalii varied along altitudes, and such differences likely play a certain role in highland adaptation. Our findings warrant a fur...Continue Reading

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Citations

Oct 23, 2018·Molecular Ecology·Taichi A SuzukiMichael W Nachman
Sep 2, 2018·The Journal of Experimental Biology·Samantha S FontaineKevin D Kohl
Aug 10, 2021·Frontiers in Microbiology·Ni HanBi Yujing
Aug 28, 2021·Animals : an Open Access Journal From MDPI·Lin ZhangBuddhi Dayananda

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Methods Mentioned

BETA
PCR
electrophoresis

Software Mentioned

vegan
WGCNA
stats
fSe
FLASH
SPSS
LE
LEfSe
QIIME
UPARSE

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