Changes in intramyocardial ST segment voltage and gas tensions with regional myocardial ischemia in the dog.

Circulation Research
S F KhuriV L Gott

Abstract

This study was designed to evaluate the sensitivity of changes in myocardial carbon dioxide and oxygen tensions as indicators of regional myocardial ischemia and also to determine to what extent these changes can be related to changes in intramyocardial ST segment voltage. Changes in ST segment voltage recorded in unipolar epicardial electrodes proved to be a less-sensitive indicator of underlying myocardial ischemia than were changes in ST segment voltage recorded in unipolar intramyocardial electrodes. In 9 dogs, regional ischemia was produced by placing a variable constrictor on the left circumflex coronary artery; circumflex flow was monitored. Myocardial carbon dioxide and oxygen tensions were measured using a mass spectrometer. Unipolar electrograms were recorded using a multicontact plunge electrode. With progressive degrees of proximal stenosis, ranging from a critical stenosis, which is associated with a decrease in mean flow of less than 15%, to a severe stenosis associated with and 80% decrease, ST voltage increased 21 mv and carbon dioxide tension increased 84 mm Hg, but oxygen tension decreased only 7 mm Hg. The study suggests that increases in intramyocardial ST segment voltage, an index of myocardial ischemia, ar...Continue Reading

References

Feb 1, 1972·Journal of Applied Physiology·J W BrantiganM N Martz
Jul 1, 1968·Cardiovascular Research·A J Moss
Mar 1, 1967·The American Journal of Physiology·N Brachfeld, J Scheuer
Dec 1, 1964·American Heart Journal·D DURRERJ BUELLER

❮ Previous
Next ❯

Citations

Jun 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·H P ShuklaP P Antich
Oct 1, 1984·Biulleten' eksperimental'noĭ biologii i meditsiny·G Kh Goldshteĭne, G G Chichkanov
Jan 1, 1988·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·M E UpsherH R Weiss
Nov 1, 1978·Basic Research in Cardiology·D StewartJ Wikman-Coffelt
Jan 10, 2002·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Yoanna K Skrobik, Janos G Filep
Dec 1, 1995·International Journal of Cardiology·M Fujita
Jan 16, 2002·The Annals of Thoracic Surgery·K R KhabbazK G Warner
Nov 1, 1981·The Annals of Thoracic Surgery·S K LucasT J Gardner
Jul 1, 1995·Journal of Electrocardiology·S HorinakaS Yagi
Dec 1, 1984·Journal of Molecular and Cellular Cardiology·R BolliR R Miller
Mar 1, 1987·Journal of Molecular and Cellular Cardiology·J G MurphyJ D Marsh
Aug 26, 1998·International Journal of Cardiology·S Horinaka, H Yamamoto
Feb 1, 1990·Journal of the American College of Cardiology·R J GazmuriE C Rackow
Apr 28, 1977·The New England Journal of Medicine·L D Hillis, E Braunwald
Jul 1, 1979·Archives of Environmental Health·L C Becker, E D Haak
Feb 1, 1979·Australian and New Zealand Journal of Medicine·P L Thompson
Mar 1, 1993·Journal of Cardiac Surgery·S F KhuriN A Healey
Oct 1, 1982·British Heart Journal·M S ElaminR J Linden
Oct 1, 1993·The American Review of Respiratory Disease·H Zhang, J L Vincent
Mar 8, 2016·Journal of Electrocardiology·Kedar ArasRob MacLeod
Oct 19, 2011·Journal of Molecular and Cellular Cardiology·Andreas DeussenWilliam Chilian
Feb 1, 1981·The Annals of Thoracic Surgery·B BrandtJ L Ehrenhaft
May 30, 2007·The Journal of Thoracic and Cardiovascular Surgery·Dharam J KumbhaniShukri F Khuri
Sep 30, 2014·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Antonio Bayés de LunaHein Wellens
Nov 1, 1977·The American Journal of Cardiology·J D HearseG Boulle
Jul 1, 1977·The American Journal of Cardiology·R P Holland, H Brooks
Jan 29, 2005·The Journal of Thoracic and Cardiovascular Surgery·Shukri F KhuriWilliam G Henderson
Jun 1, 1981·The American Journal of Cardiology·B R Chaitman, J S Hanson
Jun 1, 1981·The American Journal of Cardiology·B R ChaitmanJ S Hanson
Nov 18, 2004·American Journal of Surgery·Dharam J KumbhaniShukri F Khuri
Aug 10, 2004·Surgery·Dharam J KumbhaniShukri F Khuri
Jan 1, 1979·The American Journal of Cardiology·L H OpieW F Lubbe
Sep 1, 1986·The American Journal of Cardiology·N ReifartS F Khuri
Jan 1, 1983·International Journal of Cardiology·S C DennisD J Hearse
May 1, 1990·International Journal of Cardiology·M FujitaD Franklin
Oct 1, 1987·The Journal of Surgical Research·S Y SiouffiS F Khuri
Jan 1, 1988·American Heart Journal·R Bolli, B Patel
Jan 1, 1988·Journal of Electrocardiology·M FujitaD Franklin
Nov 1, 1982·Pacing and Clinical Electrophysiology : PACE·S SiegelS Furman

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