Changes in levels of mucosal glycoprotein on cysteamine-induced duodenal ulcers in rats

Scandinavian Journal of Gastroenterology. Supplement
K KogaS Ashizawa

Abstract

Duodenal ulcers were induced in rats by cysteamine administration. Time-course changes in duodenal hexosamine, blood flow and intragastric pH were measured, as well as changes in the susceptibility of Brunner's glands to concanavalin A (Con A) staining. Hexosamine contents in the duodenum decreased significantly at 5 and 24 h. In the control group, Brunner's glands were stained brown using Con A staining. One day after cysteamine administration, the extent of Con A staining markedly decreased. At 3 and 7 days, gland susceptibility to staining was essentially the same as that of the control group.

References

Apr 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·T Katsuyama, S S Spicer

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