PMID: 2506377Jul 1, 1989Paper

Changes in liver function tests in patients with inflammatory bowel disease on enteral nutrition

JPEN. Journal of Parenteral and Enteral Nutrition
C DolzM A Gassull

Abstract

Morphologic and functional hepatic changes occur in inflammatory bowel disease (IBD). Patients with this disease often require the administration of artificial nutritional support. Liver function tests (LFT) derangement is a widely recognized side-effect of total parenteral nutrition (TPN). Therefore, the use of this modality of nutritional support may be an additional factor to cause hepatic damage in IBD patients. However whether or not the same occurs in patients receiving total enteral nutrition (TEN) is not well-established. The aim of the present study was to evaluate the effect of TEN upon LFT in patients with moderate to severe acute attacks of IBD, by means of a prospective, controlled, and nonrandomized design. Forty-nine patients were included; 29 (11 patients with ulcerative colitis and 18 with Crohn's disease) received TEN, and 20 (11 with ulcerative colitis and 9 with Crohn's disease) did not. Both groups were homogeneous regarding age, sex, disease activity index, nutritional status, and length of the study (24.8 +/- 1.3 vs 23.9 +/- 16.8 days). In all cases, weekly measurements of serum alkaline phosphatase, GOT, and GPT were performed. There were no significant differences in LFT at the beginning of the study be...Continue Reading

References

Jun 1, 1979·JAMA : the Journal of the American Medical Association·K D LindorM A Hirschkorn
Mar 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·J F RobertsonA Shenkin
Nov 1, 1986·Gut·M A GassullC Dolz
Jan 1, 1985·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J M BengoaI H Rosenberg
May 1, 1985·JPEN. Journal of Parenteral and Enteral Nutrition·G NeidichH L Sharp
Nov 21, 1985·The New England Journal of Medicine·B R Brown
Apr 1, 1971·The Quarterly Journal of Medicine·A D PerrettR Wright
Apr 1, 1971·The Quarterly Journal of Medicine·A D PerrettR Wrigth
Mar 8, 1980·Lancet·R F Harvey, J M Bradshaw
Sep 1, 1983·JPEN. Journal of Parenteral and Enteral Nutrition·W W KingR A Malt
Jan 1, 1980·Digestive Diseases and Sciences·C O ElsonI H Rosenberg
Apr 1, 1980·Gut·P A van HeesJ H van Tongeren
Jun 1, 1964·The American Journal of Medicine·W L PALMERS S FUENTES
Jul 1, 1965·Annals of Internal Medicine·S P MISTILISS J GOULSTON
Jul 1, 1965·Annals of Internal Medicine·S P MISTILIS

❮ Previous
Next ❯

Citations

Sep 1, 1993·Digestive Diseases and Sciences·F KurokiM Fujishima
Sep 1, 2005·International Journal of Colorectal Disease·Julie C CarrierJohane P Allard
Dec 1, 1995·Free Radical Biology & Medicine·G D Buffinton, W F Doe
Nov 5, 2003·Advanced Drug Delivery Reviews·Amy B ForakerPeter W Swaan
May 15, 2013·Clinical Oral Investigations·Goknur KalkanSerbulent Yigit
Jun 12, 2009·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·André Van GossumUNKNOWN ESPEN
Jun 1, 1995·Journal of the American College of Nutrition·E R Briones, F L Iber
Jul 6, 2010·Journal of Pediatric Gastroenterology and Nutrition·Ellen Schatorjé, Hans Hoekstra

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society
S J H BrookesVarenna Group
© 2022 Meta ULC. All rights reserved