Changes in multifinger interaction and coordination in Parkinson's disease.

Journal of Neurophysiology
Jaebum ParkMark L Latash

Abstract

In this study, we tested several hypotheses related to changes in finger interaction and multifinger synergies during multifinger force production tasks in Parkinson's disease. Ten patients with Parkinson's disease, mostly early stage, and 11 healthy control subjects participated in the study. Synergies were defined as covaried adjustment of commands to fingers that stabilized the total force produced by the hand. Both Parkinson's disease patients and control subjects performed accurate isometric force production tasks with the fingers of both the dominant and nondominant hands. The Parkinson's disease patients showed significantly lower maximal finger forces and higher unintended force production (enslaving). These observations suggest that changes in supraspinal control have a major effect on finger individuation. The synergy indexes in the patients were weaker in both steady-state and cyclic force production tasks compared with the controls. These indexes also were stronger in the left (nondominant) hand in support of the dynamic-dominance hypothesis. Half of the patients could not perform the cyclic task at the highest frequency (2 Hz). Anticipatory adjustments of synergies prior to a quick force pulse production were delay...Continue Reading

References

Jan 1, 1992·Annual Review of Neuroscience·W T ThachJ G Keating
Jan 1, 1988·Annals of the New York Academy of Sciences·M WoollacottD Manchester
Dec 1, 1986·Brain : a Journal of Neurology·G E StelmachE A Strand
Feb 1, 1972·Journal of the Neurological Sciences·J E McLennanR S Schwab
Sep 15, 1994·The Journal of Physiology·S L Kilbreath, S C Gandevia
Dec 1, 1995·Current Opinion in Neurobiology·A M Graybiel
Oct 6, 1998·Motor Control·I M Gelfand, M L Latash
Jun 4, 1999·Brain : a Journal of Neurology·H ForssbergL Dubowitz
Jun 26, 1999·Experimental Brain Research·J P Scholz, G Schöner
Mar 4, 2000·The Journal of Physiology·F DanionV M Zatsiorsky
Apr 15, 2000·Experimental Brain Research·V M ZatsiorskyM L Latash
Nov 8, 2001·Journal of Neurophysiology·M H Schieber
Nov 20, 2001·Experimental Brain Research·M L LatashG Schöner
Jan 22, 2002·Exercise and Sport Sciences Reviews·Mark L LatashGregor Schöner
Jan 25, 2002·Experimental Brain Research·Robert L Sainburg
Oct 23, 2002·Journal of Applied Physiology·Minoru ShinoharaMark L Latash
Sep 6, 2003·Brain : a Journal of Neurology·Darcy S Reisman, John P Scholz
Mar 9, 2004·Journal of Applied Physiology·Jae Kun ShimMark L Latash
May 11, 2004·Journal of Applied Physiology·Marc H Schieber, Marco Santello
Jan 5, 2005·Brain and Cognition·Christopher P BertramGeorge E Stelmach
May 11, 2005·Neuroscience Letters·Halla OlafsdottirMark L Latash
May 26, 2005·Biological cybernetics·James C Houk
Oct 5, 2006·Neuroscience Letters·Wei ZhangMark L Latash
Oct 19, 2006·Clinical Biomechanics·Halla OlafsdottirMark L Latash
Jan 16, 2007·NeuroImage·Hong YuDavid E Vaillancourt
Jul 13, 2007·Brain : a Journal of Neurology·Sydney Y SchaeferRobert L Sainburg
Aug 24, 2007·Motor Control·Mark L LatashGregor Schöner
Oct 3, 2007·Experimental Brain Research·Lisa M MuratoriMarco Santello
Jan 21, 2009·Experimental Brain Research·Paolo VivianiPhilippe Vindras
Mar 12, 2009·Experimental Brain Research·Laetitia FradetNatalia Dounskaia
May 12, 2009·Neuroscience and Biobehavioral Reviews·Janey ProdoehlDavid E Vaillancourt
Feb 10, 2010·Experimental Brain Research·Frederic AlbertAndrew M Gordon
Apr 2, 2010·Journal of Neurophysiology·Tarkeshwar SinghMark L Latash
Aug 13, 2010·Motor Control·Mark L Latash
Nov 12, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Claire L TomlinsonCarl E Clarke
May 4, 2011·Experimental Brain Research·Vennila KrishnanMark L Latash

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Citations

Feb 16, 2013·Experimental Brain Research·Yen-Hsun WuMark L Latash
Mar 16, 2013·Experimental Brain Research·Tao ZhouMark L Latash
Jun 6, 2013·Experimental Brain Research·Pinar Arpinar-AvsarMark L Latash
Aug 15, 2013·Experimental Brain Research·Jaebum ParkMark L Latash
Dec 15, 2012·Journal of Motor Behavior·Yen-Hsun WuMark L Latash
Jun 8, 2013·Journal of Motor Behavior·Joel R MartinVladimir M Zatsiorsky
Aug 15, 2014·European Journal of Applied Physiology·Yun WangFatao Wan
Nov 6, 2014·Experimental Brain Research·Hang Jin JoMark L Latash
Jun 2, 2015·Perceptual and Motor Skills·Jaebum ParkJae Kun Shim
Dec 24, 2013·Human Movement Science·Luke A WilhelmVladimir M Zatsiorsky
Nov 5, 2014·Journal of Motor Behavior·Yen-Hsun WuMark L Latash
Oct 8, 2016·Journal of Motor Behavior·Hang Jin JoMark L Latash
Jan 23, 2017·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Ali FalakiMark L Latash
Apr 11, 2017·Computer Methods and Programs in Biomedicine·Andrea VianelloRiccardo Budai
Jun 15, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Hang Jin JoMark L Latash
May 20, 2016·Journal of Neurophysiology·Behnoosh ParsaMark L Latash
Mar 29, 2018·Journal of Neurophysiology·Mark L Latash
Jul 20, 2018·Experimental Brain Research·Mitchell Tillman, Satyajit Ambike
Sep 16, 2017·Journal of Motor Behavior·Mariusz P FurmanekMark L Latash
Apr 10, 2013·Experimental Brain Research·Nejc SarabonMark L Latash
Nov 6, 2013·Exercise and Sport Sciences Reviews·Yen-Hsun Wu, Mark L Latash
Sep 26, 2014·Journal of Neurophysiology·Sasha ReschechtkoMark L Latash
Jan 26, 2020·Motor Control·Mark L Latash
Sep 8, 2016·Experimental Brain Research·Sasha ReschechtkoMark L Latash
Jun 6, 2014·Journal of Neurophysiology·Alexander N KlishkoBoris I Prilutsky
Sep 5, 2020·Journal of Motor Behavior·Cristian CuadraMark L Latash
Feb 9, 2017·Experimental Brain Research·Stanislaw SolnikMark L Latash
Jul 5, 2017·Frontiers in Human Neuroscience·Jaebum Park, Dayuan Xu
Apr 25, 2014·Journal of Neurophysiology·Joseph SniderHoward Poizner
Nov 28, 2012·Journal of Applied Biomechanics·Joel R MartinVladimir M Zatsiorsky
May 10, 2017·Experimental Brain Research·Omid RasouliMark L Latash

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