Changes in neutrophil, lymphocyte, platelet ratios and their relationship with NIHSS after rtPA and/or thrombectomy in ischemic stroke

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Hatice Ferhan KömürcüÇisil İrem Özgenç Bi Er

Abstract

Various reactive oxygen radicals and inflammatory mediators emerge in ischemic stroke, and changes occur in the number of leukocytes and platelets. Variations in the counts and ratios of these cells may be related to the early and late course and prognosis of stroke. In this study, the relationship between changes in counts or ratios of neutrophil, lymphocyte, platelet, and National Health Institute Stroke Scale (NIHSS) scores was investigated in patients who presented with an ischemic stroke and treated with recombinant tissue plasminogen activator (rtPA) and/or thrombectomy. Changes in neutrophil, lymphocyte, platelet counts; neutrophil-to-leukocyte ratio (NLR), neutrophil-to-lymphocyte ratio, platelet-to-leukocyte ratio (PLR), and platelet-to- lymphocyte ratio between day of admission (day 0), and 1st, 3rd, and 7th days after application of treatment modalities in 296 patients presented with acute ischemic stroke who underwent rtPA within the first 4,5 hours and / or thrombectomy within 6 hours after stroke and the relationship between these changes and the NIHSS (National Health Institute Stroke Scale) scores were evaluated retrospectively. In our study, leukocyte and neutrophil counts were higher on the first day after acu...Continue Reading

Citations

Sep 11, 2021·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Xifang ZhangQiujing Wang
Jul 1, 2021·Acta Neurologica Scandinavica·Divyansh SharmaSonu Menachem Maimonides Bhaskar

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