Changes in Pain Sensitization After Bariatric Surgery.

Arthritis Care & Research
Joshua J StefanikTuhina Neogi

Abstract

To evaluate changes in pain (at the knee and elsewhere) and pain sensitization in obese subjects with knee pain who were having bariatric surgery compared with similarly obese individuals who were undergoing medical management. This study included a cohort of subjects who were having bariatric surgery and those undergoing medical management. Knee pain severity of the more painful knee (index knee) was assessed at baseline and at 12 months using the Western Ontario and McMaster Universities Osteoarthritis Index. The pressure pain threshold (PPT) was evaluated at the index patella and the right wrist. Low patella PPT may reflect peripheral and/or central sensitization, and low wrist PPT may reflect central sensitization. The mean change in measures of pain and pain sensitization was analyzed in the surgery and medical management groups separately. A total of 45 subjects in the surgery group and 22 in the medical management group completed baseline and follow-up visits. The mean weight loss was 32.7 kg (29.0%) and 4.6 kg (4.1%) in the surgery and medical management groups, respectively. Knee pain decreased only in the surgery group, in which the PPT at the patella improved by 38.5% (P = 0.0007) and at the wrist by 30.9% (P = 0.005...Continue Reading

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Citations

Sep 14, 2018·Nature Reviews. Rheumatology·Francis BerenbaumDavid T Felson
Jun 26, 2020·Osteoarthritis and Cartilage·J J StefanikT Neogi
Oct 31, 2020·Nature Reviews. Rheumatology·Augustin LatourtePascal Richette
Dec 26, 2018·Joint, Bone, Spine : Revue Du Rhumatisme·Alice CourtiesJérémie Sellam
Jun 13, 2021·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Elise A F HeutsMatthijs P Somford
Nov 5, 2021·Surgical Endoscopy·Jaewhan KimTed Adams

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