Changes in perinatal care as a determinant of the level and diversity of antiinfectives use in a neonatal intensive care unit in Rio de Janeiro, Brazil

Cadernos de saúde pública
Claudia Garcia Serpa Osorio-de-CastroSelma Rodrigues de Castilho

Abstract

This study focuses on a five-year profile (1990-1994) in the utilization of antiinfectives in a neonatal intensive care unit (NICU) in Rio de Janeiro, Brazil. Total antiinfectives consumption, diversity, and possible determinants were analyzed. A descriptive, longitudinal, and retrospective drug utilization study design was adopted. Document research, observation, and semi-structured interviews provided information on the neonatal intensive care provided, and drug supply and daily hospital records provided data on antiinfectives use, based on the Anatomical Therapeutic Chemical (ATC) classification and the infant defined daily dose (DDDi) as units of measurement. The numerical results suggest an increase in total consumption of antiinfectives and a decrease in their diversity. Analyzed in view of the institutional profile and rational drug use, these results indicate that changes in the type of care provided during the study period were key determinants of antiinfectives use.

References

Oct 8, 1999·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·P J Schneider
Jan 15, 2000·Archives of Disease in Childhood. Fetal and Neonatal Edition·S WhyteJ Wyllie
Apr 29, 2000·Journal of Clinical Epidemiology·F D FuchsP K Whelton
Sep 16, 2000·Intensive Care Medicine·J E FischerS Fanconi
Sep 23, 2000·The Pediatric Infectious Disease Journal·R F Jacobs
Feb 15, 2001·Archives of Pediatrics & Adolescent Medicine·K J Anand, UNKNOWN International Evidence-Based Group for Neonatal Pain
Feb 24, 2001·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·L T Kohn
Feb 24, 2001·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·P J Schneider

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Citations

Aug 8, 2007·Ciência & saúde coletiva·Rachel Magarinos-TorresVera Lucia Edais Pepe

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