Changes in perioperative hemoglobin and hematocrit in patients undergoing total knee arthroplasty: a prospective observational study of optimal timing of measurement.

The Journal of International Medical Research
Chenrong KeMochuan Chen

Abstract

This study was performed to depict the patterns of change in the perioperative hemoglobin (Hb) concentration and hematocrit (Hct) and to identify the optimal timing of Hb and Hct measurement in patients undergoing total knee arthroplasty (TKA). This prospective observational study involved 302 consecutive patients who underwent TKA. The patients were kept in hospital for 1 full week postoperatively. Hb and Hct measurements were performed preoperatively and on days 1 to 7 postoperatively and then during clinic visits at 1, 3, and 6 months postoperatively. The Hb concentration and Hct decreased during the first few days postoperatively and reached a nadir on postoperative day 4 and 3, respectively; they then recovered in the following days. Significant differences in the Hb concentration and Hct were detected between the preoperative period and day 1, between days 1 and 2, between days 2 and 3, between day 7 and 1 month, and between 1 and 3 months. A significant difference in the Hct was also detected between 3 and 6 months. The optimal timing of Hb and Hct measurement is on postoperative day 3 or 4. This timing accurately reflects ongoing hidden blood loss to better guide blood transfusions.

References

Jun 21, 2002·Transfusion Medicine Reviews·Jeffrey L CarsonDavid Henry
Apr 9, 2005·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Keyvan KarkoutiRoderrick Davey
Nov 11, 2011·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Sheraz R MarkarRahul V Patel
Nov 9, 2012·The Journal of Bone and Joint Surgery. British Volume·C D Watts, M W Pagnano
Aug 21, 2013·The Journal of Knee Surgery·Samik BanerjeeMichael A Mont
Jun 4, 2014·The Journal of Arthroplasty·Hiroyuki Yoshihara, Daisuke Yoneoka
Jul 11, 2014·The Journal of Arthroplasty·Nicholas B FrischCraig D Silverton
Dec 5, 2014·The Journal of Bone and Joint Surgery. American Volume·Adam HartJohn Antoniou
Feb 24, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Peng-Fei ShenYu-Xing Qu
Feb 20, 2016·The Journal of Nutrition, Health & Aging·K-I KimH J Chin
Sep 11, 2016·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Rahel MeierHans Rickli
Nov 7, 2016·Journal of Bodywork and Movement Therapies·Cirlene de Lima MarinhoAgnaldo José Lopes
Feb 24, 2017·Knee Surgery & Related Research·Mahdi Yacine KhalfaouiMichael C P Wilkinson
Mar 16, 2017·The Journal of Bone and Joint Surgery. American Volume·Emmanuel ThienpontPeter Fennema
Jun 4, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Pengfei ZanGuodong Li
Jul 25, 2017·The Journal of Arthroplasty·Matthew D MitchellCraig A Umscheid
Aug 7, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Pengfei ZanGuodong Li
Feb 10, 2018·Orthopaedic Surgery·Qiang LuDong Yin
Dec 14, 2018·Transfusion Medicine·E LaurénV Pettilä

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