Changes in quality of life of head-and-neck cancer patients following postoperative radiotherapy

Acta Oncologica
Fu-Min FangChong-Jong Wang

Abstract

The purpose of this study was to investigate the longitudinal changes in quality of life (QoL) for 77 head-and-neck squamous cell cancer (HNSCC) patients receiving postoperative radiotherapy (RT). The data pertaining to their QoL were collected using the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30) and the EORTC Head and Neck Module (QLQ-H&N35) before and two years after postoperative RT. The differences in all the QLQ-C30 scales between the two time points were not statistically (p<0.01) or clinically (difference > or =+10 points) significant. Of all the scales in the QLQ-H&N35, only problems in social eating, teeth, dry mouth, and sticky saliva became worse with both statistical and clinical significance. Clinical cancer stage and marital status were the only variables significantly associated with the change in global QoL. The subjects with stage IV disease (5.0-fold) and those with a spouse (5.5-fold) had a lower risk of reporting negative changes in global QoL. The study indicates that some individual HNSCC patients, after receiving postoperative RT, suffered from a deterioration of QoL scales, especially in some specific head-and-neck symptoms. Meanwhile, we...Continue Reading

References

Jul 1, 1993·Journal of Clinical Psychology·D R EvansM E Metzen
Mar 1, 1993·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D F CellaJ Brannon
Nov 1, 1995·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Y C KoC C Tsai
Dec 1, 1996·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·M T King
Jan 24, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D OsobaJ Pater
Jul 10, 1999·Social Science & Medicine·M A Sprangers, C E Schwartz
Sep 7, 1999·International Journal of Radiation Oncology, Biology, Physics·P U HugueninC Glanzmann
Jan 26, 2000·The Laryngoscope·A de GraeffJ A Winnubst
Mar 10, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A de GraeffJ A Winnubst
Feb 19, 2002·International Journal of Radiation Oncology, Biology, Physics·Susanne SehlenEckhart Dühmke
Aug 28, 2002·Acta Oncologica·Mirjam A G Sprangers

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Citations

Jun 18, 2010·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Hsiu-Fang Lee, Hsueh-Erh Liu
Apr 6, 2007·Critical Reviews in Oncology/hematology·Barbara A MurphyMary Dietrich
Sep 3, 2011·Scandinavian Journal of Caring Sciences·Shu-Ching Chen
Sep 17, 2013·International Journal of Dental Hygiene·K A MooreC S Farah
Jan 16, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·K A PatemanC S Farah
Nov 19, 2013·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·K A MooreC S Farah
Apr 28, 2007·International Journal of Surgery·Gerry M Humphris, Gozde Ozakinci
Apr 15, 2014·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Anne SchallerBritt Larsson
Feb 6, 2007·The Laryngoscope·Irma M Verdonck-de LeeuwC Rene Leemans
Aug 8, 2007·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·K BudischewskiSt Mose
Feb 27, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Christoph BeckerKilian Konrad Kenjiro Dahlem
Mar 20, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·S B JensenUNKNOWN Salivary Gland Hypofunction/Xerostomia Section, Oral Care Study Group, Multinational Association of Supportive Care in Cance
May 25, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Allan J HovanUNKNOWN Dysgeusia Section, Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Socie
Jun 15, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Joel B EpsteinMichael T Brennan
Dec 22, 2005·The Laryngoscope·Helmut AbendsteinKristin Bjordal
Sep 13, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Peter A PellioniszMaie A St John
Nov 29, 2012·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Susanne SingerDirk Hofmeister
Nov 20, 2019·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Yojana SharmaVibhuti Parikh
Sep 21, 2018·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Hani Z MarzoukiHadi Seikaly

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