Changes in red blood cell transfusion practice during the past quarter century: a retrospective analysis of pediatric patients undergoing elective scoliosis surgery using the Mayo database

The Spine Journal : Official Journal of the North American Spine Society
Timothy R LongC Thomas Wass

Abstract

Previous studies have demonstrated significant changes in red blood cell (RBC) transfusion practice over several decades. The purpose of the present study was to ascertain changes in transfusion practice during a 25-year study epoch and determine whether these changes had any impact on the frequency of perioperative morbidity and mortality in pediatric patients undergoing major spine surgery. Retrospective chart review. Pediatric patients undergoing elective scoliosis surgery. Impact of RBC transfusion on perioperative morbidity and mortality. Pediatric patients undergoing elective scoliosis surgery were stratified into one of two transfusion-related groups: 1975 to 1985 (ie, pre-human immunodeficiency virus screening, early practice group, n=177) or 1990 to 2000 (ie, recent practice group, n=192). Transfusion and perioperative outcome data were obtained from medical records. Red blood cell use was analyzed as a continuous variable and compared between groups using the Wilcoxon rank sum test, as were preoperative, postoperative, and discharge hemoglobin concentration. Age-adjusted data were compared between groups using chi-square or Fisher exact tests. Patients in the recent practice group had significantly worse comorbid dise...Continue Reading

References

Aug 26, 1998·Transfusion·D O WarnerP Santrach
Dec 14, 2002·Mayo Clinic Proceedings·Gregory A NuttallDavid O Warner
Nov 1, 2003·The Spine Journal : Official Journal of the North American Spine Society·Michael G VitaleDavid P Roye
Feb 27, 2007·Transfusion·Marian T SullivanEdward L Wallace
Jul 27, 2007·Best Practice & Research. Clinical Anaesthesiology·Aryeh ShanderDonat R Spahn

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Citations

Jun 10, 2014·The Spine Journal : Official Journal of the North American Spine Society·Dmitri van PoptaRajat Verma
Jul 23, 2013·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Pilar SolvesMiguel Angel Sanz
Aug 4, 2012·The Spine Journal : Official Journal of the North American Spine Society·Meghan N Imrie
Oct 9, 2012·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·C LejusD Péan
Oct 9, 2018·Paediatric Anaesthesia·Courtney E BakerJonathan G Schoenecker
Dec 9, 2016·Spine Deformity·Lindsay M AndrasDavid L Skaggs
Feb 26, 2013·Journal of Neurosurgical Anesthesiology·Jeffrey J Pasternak, William L Lanier
Mar 7, 2014·Journal of Neurosurgical Anesthesiology·Jeffrey J Pasternak, William L Lanier
Apr 27, 2021·Spine Deformity·Mark J McVeyR Zeller

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