Abstract
Previous studies have demonstrated significant changes in red blood cell (RBC) transfusion practice over several decades. The purpose of the present study was to ascertain changes in transfusion practice during a 25-year study epoch and determine whether these changes had any impact on the frequency of perioperative morbidity and mortality in pediatric patients undergoing major spine surgery. Retrospective chart review. Pediatric patients undergoing elective scoliosis surgery. Impact of RBC transfusion on perioperative morbidity and mortality. Pediatric patients undergoing elective scoliosis surgery were stratified into one of two transfusion-related groups: 1975 to 1985 (ie, pre-human immunodeficiency virus screening, early practice group, n=177) or 1990 to 2000 (ie, recent practice group, n=192). Transfusion and perioperative outcome data were obtained from medical records. Red blood cell use was analyzed as a continuous variable and compared between groups using the Wilcoxon rank sum test, as were preoperative, postoperative, and discharge hemoglobin concentration. Age-adjusted data were compared between groups using chi-square or Fisher exact tests. Patients in the recent practice group had significantly worse comorbid dise...Continue Reading
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