PMID: 9555826Apr 29, 1998Paper

Changes in red cell transfusion practice among adult trauma victims

The Journal of Trauma
K J FarionJ P Szalai

Abstract

Recent attention concerning the adverse outcomes of blood transfusion has resulted in decreased blood product usage for nonemergency care. We hypothesized that there has also been a decrease in blood product use in the management of seriously injured adults. A retrospective review of institutional database records was conducted at a regional trauma center for adults admitted during 1991, 1993, and 1995. Data was analyzed for trends in amount, type, and timing of blood product use. A total of 1,738 patients were assessed, with 1,605 meeting inclusion. The three patient groups were similar, including injury severity (overall mean Injury Severity Score of 23.6), mechanism (88% blunt), and survival (87%). In 1991, 54% of the patients were transfused a total of 2,341 units of packed red blood cells (mean 4.67 units/pt treated) versus 42% of patients in 1995 (p < 0.0001) who received 2,018 packed red blood cells (mean 3.57 units/patient treated, p = 0.05). A significantly higher proportion of units was transfused in the first 24 hours of care in 1995 (64%) compared with 1991 (21%, p < 0.0001). A reduction in the use of universal donor type-O blood use was also found (1.21 vs. 0.65 units/patient transfused, p < 0.0001). Despite simila...Continue Reading

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Citations

Oct 12, 2002·Journal of the American College of Surgeons·Steven A GouldGerald S Moss
Oct 21, 2006·Current Opinion in Hematology·Eilat ShinarBarbara G Silverman
Jun 10, 2006·The Journal of Trauma·Brian J EastridgeJohn B Holcomb
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Jul 2, 2009·Transfusion Medicine·Marc MaegeleUNKNOWN Working Group on Polytrauma of the German Trauma Society (DGU)
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Feb 16, 2006·Injury·Elizabeth BealeDemetrios Demetriades
May 12, 2004·Critical Care Clinics·Carl I Schulman, Stephen M Cohn
May 12, 2004·Critical Care Clinics·Aryeh Shander
Nov 5, 2004·Hospital Medicine·Colin F Mackenzie, Cyndi Bucci
Jan 6, 2006·The Journal of Trauma·Richard P DuttonThomas M Scalea

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