PMID: 11333838May 3, 2001Paper

Changes in regional fat redistribution and the effects of estrogen during spontaneous weight gain in women with anorexia nervosa

The American Journal of Clinical Nutrition
Steven GrinspoonAnne Klibanski

Abstract

Anorexia nervosa is a disease of severe acquired undernutrition with a high and increasing prevalence among young women in the United States. The objective was to investigate the effects of spontaneous outpatient weight recovery and estrogen administration on fat distribution in patients with anorexia nervosa. Twenty-seven amenorrheic women aged 26.6 +/- 1.2 y with anorexia nervosa were identified through an outpatient study of bone loss and were randomly assigned to receive or not receive estrogen without any dietary intervention other than calcium and multivitamin supplements. Body composition was measured at baseline and at 6 and 9 mo and was compared with cross-sectional values obtained in 20 healthy, eumenorrheic, age-matched (25.4 +/- 0.5 y) control subjects. Twenty of the 27 patients with anorexia aged 27.0 +/- 1.3 y spontaneously gained weight (4.1 +/- 0.9 kg); body mass index (in kg/m(2)) increased from 16.1 +/- 0.3 to 17.5 +/- 0.4. Fat mass and lean mass accounted for 68% and 32% of the gain in total body mass, respectively. With spontaneous weight gain, there was a significant increase in the percentage of trunk fat from 32.4 +/- 1.3% at baseline to 36.5 +/- 1.0% at 9 mo (P = 0.03), which correlated with urinary free...Continue Reading

References

Jan 27, 1977·The New England Journal of Medicine·R M BoyarD K Fukushima
Dec 1, 1991·Metabolism: Clinical and Experimental·J HaarboC Christiansen
Jul 1, 1991·The American Journal of Psychiatry·A R LucasL T Kurland
Jun 1, 1990·The American Journal of Clinical Nutrition·R B MazessJ Hanson
Sep 1, 1990·The American Journal of Clinical Nutrition·R B MazessE S Ohlrich
Mar 1, 1989·The Journal of Clinical Endocrinology and Metabolism·B M BillerA Klibanski
Jan 1, 1996·The International Journal of Eating Disorders·T A WaddenA M Conill
Jan 1, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M ZamboniO Bosello
Apr 1, 1997·The American Journal of Clinical Nutrition·C I OrphanidouA S Belzberg
Aug 11, 1999·The International Journal of Eating Disorders·T IketaniS Yamagami
Nov 21, 2000·Annals of Internal Medicine·S GrinspoonA Klibanski

❮ Previous
Next ❯

Citations

Jun 7, 2003·The American Journal of Clinical Nutrition·Madhusmita MisraAnne Klibanski
Jul 23, 2004·International Journal of Adolescent Medicine and Health·Neville H Golden, Wendy Meyer
Feb 13, 2009·The American Journal of Clinical Nutrition·Verena K HaasKevin J Gaskin
Feb 6, 2013·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A Bosy-WestphalM J Müller
Aug 15, 2019·Adipocyte·Loes M H ElemansJames E N Minchin
Jan 16, 2020·Clinical Reviews in Bone and Mineral Metabolism·Pouneh K Fazeli
Aug 12, 2020·Translational Psychiatry·Ileana SchmalbachKatja Petrowski
Mar 22, 2006·Pediatric Research·Madhusmita MisraAnne Klibanski
Apr 21, 2004·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·P Tothill, W James Hannan
Jan 15, 2008·BJOG : an International Journal of Obstetrics and Gynaecology·Y JayasingheM Zacharin
Oct 14, 2008·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Metella DeiAlessandro Pasqua
Nov 28, 2013·Current Opinion in Endocrinology, Diabetes, and Obesity·Vibha SinghalAnne Klibanski
Oct 16, 2015·Einstein·Yara Lucy FidelixWagner Luiz do Prado
Mar 10, 2016·Hormone Molecular Biology and Clinical Investigation·Heather C M AllawayMary Jane De Souza
Aug 30, 2016·The International Journal of Eating Disorders·Laura Al-Dakhiel WinklerRené Klinkby Støving
Feb 13, 2002·European Journal of Clinical Nutrition·L ScalfiF Contaldo
Jun 7, 2002·The Journal of Clinical Endocrinology and Metabolism·Steven GrinspoonAnne Klibanski
Jan 27, 2009·Eating and Weight Disorders : EWD·C PriceH Lacey
May 8, 2009·European Journal of Nutrition·Julia EnglChristoph F Ebenbichler
Dec 25, 2008·The International Journal of Eating Disorders·Jocilyn E DellavaDaniel J Hoffman
Sep 12, 2015·The American Journal of Clinical Nutrition·Laura A BernerMichael R Lowe
Apr 18, 2012·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Pouneh K FazeliAnne Klibanski
Sep 2, 2003·The International Journal of Eating Disorders·Elisabet WentzMaria Råstam
May 3, 2001·The American Journal of Clinical Nutrition·L Mayer
Nov 28, 2013·Endocrine·Giacomo TirabassiGiorgio Arnaldi
Jan 24, 2015·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A Bosy-WestphalM J Müller
Sep 22, 2011·Journal of Pediatric Endocrinology & Metabolism : JPEM·Kathryn E AckermanMadhusmita Misra
Nov 5, 2016·Nature Reviews. Endocrinology·Melanie Schorr, Karen K Miller
Feb 7, 2018·The International Journal of Eating Disorders·Guido K W FrankElizabeth A Lawson
Sep 13, 2019·The International Journal of Eating Disorders·Christopher HübelGerome Breen
Jun 11, 2008·Nature Clinical Practice. Endocrinology & Metabolism·Elizabeth A Lawson, Anne Klibanski
Jan 14, 2011·Neuroendocrinology·Madhusmita Misra, Anne Klibanski
Sep 25, 2014·Nutrients·Marwan El GhochRiccardo Dalle Grave
Jun 9, 2005·The American Journal of Clinical Nutrition·Laurel MayerDeborah Glasofer
Jun 28, 2006·Eating and Weight Disorders : EWD·F JacoangeliM R Bollea
Oct 2, 2009·The American Journal of Clinical Nutrition·Laurel E S MayerB Timothy Walsh
May 19, 2021·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Luigi Di FilippoCaterina Conte

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

Related Papers

The Journal of Clinical Endocrinology and Metabolism
Karen K MillerAnne Klibanski
World Review of Nutrition and Dietetics
D S McLaren
JAMA : the Journal of the American Medical Association
A Fonaroff
JAMA : the Journal of the American Medical Association
K Kaplan
© 2021 Meta ULC. All rights reserved