PMID: 3745970Oct 1, 1986Paper

Changes in serum hepatitis B virus (HBV) DNA positivity in chronic HBV infection: results of a long-term follow-up study of 138 patients

The Journal of Infectious Diseases
A AlbertiG Realdi

Abstract

In an assessment of the clinical relevance of serum hepatitis B virus (HBV) DNA testing in chronic HBV infection, changes in the presence of this marker were investigated by spot hybridization in 138 hepatitis B surface antigen (HBsAg)-positive patients with chronic liver disease who were followed up for one to eight years. Forty-one patients were treated with steroids, often with evidence of potentiation of viral replication, whereas 92 patients remained untreated and had no evidence of sigma agent infection during follow-up. Data analysis in these patients allowed us to determine the significance of testing for hepatitis B e antigen and for HBV DNA in the natural history of the infection. The findings indicate that sequential testing for serum HBV DNA may be of great importance in HBsAg chronic carriers with liver disease for adequate evaluation of HBV replication and for the contribution of HBV DNA to the clinical assessment of chronic hepatitis.

Citations

Jun 1, 1991·Journal of Medical Virology·G FattovichA Ruol
Sep 12, 2000·Current Gastroenterology Reports·F Yao, R G Gish
Jul 1, 1994·Antiviral Research·A Alberti, G Fattovich
May 31, 2007·Clinical Drug Investigation·J AreiasC Teixeira
Apr 1, 1990·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·H HofmannC Kunz
Apr 1, 1988·Journal of Medical Virology·H W PengB N Chiang
Jun 1, 1988·Journal of Medical Virology·G HessK H Meyer zum Büschenfelde
Oct 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·P I LeeD S Chen
Aug 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A AlbertiA Ruol
Sep 25, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J L DienstagN Brown
Apr 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·H HagiwaraT Kamada
Sep 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A S Lok, O C Ma
Nov 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G FattovichA Alberti
Nov 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G FattovichG Realdi
Apr 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G FattovichG Busatto
Jan 1, 1996·International Journal of Clinical & Laboratory Research·G GiustinaM Plebani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

British Medical Journal
E A Williams
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
R J Fontana, A S Lok
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
G FattovichG Realdi
© 2021 Meta ULC. All rights reserved