PMID: 8938350Feb 1, 1996Paper

Changes in splenic volume after partial splenic embolization in children

Journal of Pediatric Surgery
Y WatanabeT Noda

Abstract

The authors studied changes in splenic volume after partial splenic embolization (PSE) in children who had thrombocytopenia caused by splenomegaly. Five children with hypersplenism (ages of 1, 6, 7, 10, and 14 years) underwent PSE. The follow-up period ranged from 1 month to 8 years 9 months. Whole and infarcted splenic volumes were measured from computed tomography images obtained before and after PSE. Within 2 weeks after PSE, the whole splenic volume increased to 110% to 140% of the pre-PSE volume. The infarcted area disappeared 3 to 4 months after PSE, and the whole splenic volume decreased markedly. The decreased volume tended to be stable during the follow-up period. The splenic enlargement before PSE ranged from 7.2 to 14.2 times the standard splenic volume for a corresponding body weight. The splenic volume did not become normal after PSE; it remained between 2 and 7 times larger than standard. Platelet counts stayed above 10 x 10(4) /mm3 when the splenic volume reduced to 2 times the standard volume. The first 4 weeks after PSE is the most dangerous period for the development of splenic capsule. The infarcted parenchyma is absorbed 3 to 4 months after PSE, and the whole splenic volume is reduced. Thereafter, the spleni...Continue Reading

References

Jul 1, 1989·Journal of Pediatric Surgery·C T BrandtJ R Lilly
May 1, 1985·Radiology·D A KumpeG P Stellin
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Mar 1, 1994·Acta Radiologica·P Prassopoulos, D Cavouras
Jan 1, 1994·The Journal of Pediatrics·D M IsraelR R Phillips

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Citations

Dec 30, 2014·TheScientificWorldJournal·Yong-Song Guan, Ying Hu
Oct 18, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·David C MadoffMarshall E Hicks
Feb 19, 2014·Journal of Vascular and Interventional Radiology : JVIR·Stephen R PreeceCharles Y Kim
Nov 10, 2015·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Ahmed Z HelalyElsayed E Abdelaal
Nov 22, 2007·European Journal of Haematology·Barbara PratlChristian Urban

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