Changes in stress, substance use and medication beliefs are associated with changes in adherence to HIV antiretroviral therapy

AIDS and Behavior
Tyler FrenchBruce Agins

Abstract

Stress, substance use and medication beliefs are among the most frequently cited barriers to HIV treatment adherence. This study used longitudinal techniques to examine the temporal relationship between these barriers and adherence among clients attending treatment adherence support programs in New York State. A total of 4,155 interview pairs were analyzed across three interview transitions. Multinomial models were constructed with four-category change-based independent variables (e.g., low stress at both interviews, low stress at interview 1 and high stress at interview 2, high stress at interview 1 and low stress at interview 2, high stress at both interviews) that predicted a similarly constructed four-category adherence change variable. Clients who reported positive changes in stress, substance use, or medication beliefs were more likely to change from being nonadherent to being adherent, while clients who reported negative changes were more likely to change from being adherent to being nonadherent. To improve or maintain adherence over time, strategies should be used that facilitate positive changes-and prevent negative changes-in stress, substance use, and medication beliefs.

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Citations

Jun 12, 2012·AIDS Patient Care and STDs·Andrea NelsenAanand D Naik
Sep 17, 2013·AIDS Patient Care and STDs·Kimberly A BabsonMarcel O Bonn-Miller
Oct 12, 2012·Journal of Behavioral Medicine·Marcel O Bonn-MillerJodie A Trafton
Feb 2, 2012·AIDS Care·Luci A MartinShelley A Riggs
Dec 6, 2017·Journal of General Internal Medicine·Michael J StirrattC Ann Gakumo
Apr 23, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Chinazo O CunninghamBruce D Agins
Oct 26, 2018·BMC Research Notes·Maria Sarah NabaggalaAndrew Mujugira
Jan 1, 2016·Journal of HIV/AIDS & Social Services·Timothy J ArentsenCharles H Hinkin

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