Changes in Surgical Site Infections after Living Donor Liver Transplantation

PloS One
Masaki YamamotoSatoshi Ichiyama

Abstract

Surgical site infections (SSIs) are a major threat for liver transplant recipients. We prospectively studied SSIs after living donor liver transplantation (LDLT) at Kyoto University Hospital from April 2001 to March 2002 (1st period) and from January 2011 to June 2012 (2nd period). We investigated the epidemiology of SSIs after LDLT and determined the differences between the two periods. A total of 129 adult recipients (66 during the 1st period and 63 during the 2nd period) and 72 pediatric recipients (39 and 33) were included in this study. The SSI rates for each period were 30.3% (1st period) and 41.3% (2nd period) among the adult recipients and 25.6% and 30.3% among the pediatric recipients. The overall rates of 30-day mortality among adult transplant recipients with SSIs were 10.0% (1st period) and 3.9% (2nd period). No pediatric recipient died from SSIs after LDLT in either period. The incidence of Enterococcus faecium increased from 5.0% to 26.9% in the adults and from 10.0% to 40.0% in the pediatric patients. Extended-spectrum β-lactamase-producing Enterobacteriaceae were emerging important isolates during the 2nd period. For this period, a univariate analysis showed that ABO incompatibility (P = 0.02), total operation d...Continue Reading

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Citations

Apr 14, 2017·Transplantation Direct·Karin KatoSatoshi Ichiyama
Jul 12, 2017·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Yoichiro NatoriColeman Rotstein
May 18, 2017·Transplant International : Official Journal of the European Society for Organ Transplantation·Amr BadawyShinji Uemoto
Feb 26, 2020·Transplantation Direct·Junichi YoshikawaShinji Uemoto
Dec 1, 2020·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Laura L BioHayley A Gans
May 7, 2021·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Ming MaWentao Jiang

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