Changes in suspensions of human keratinocytes due to trypsin

Archives of Dermatological Research
S P Barton, R Marks

Abstract

Epidermal cell suspensions derived from keratotomed samples of normal human skin have been studied by light microscopy and by scanning and transmission electron microscope techniques. The method allows detailed inspection of the keratinocyte membranes. However, the trypsin used to obtain the suspensions limits the usefulness of the technique as some of the features observed - including invagination of desmosomes, vacuolation, and redistribution of tonofibrils - may be attributable to this proteolytic enzyme.

References

Jan 1, 1972·Experimental Cell Research·A BoydeP Veselý
Feb 1, 1974·Journal of Ultrastructure Research·K FukuyamaW L Epstein
Sep 1, 1972·The Journal of Investigative Dermatology·I B Stern, K H Sekeri-Pataryas
Jan 1, 1980·The British Journal of Dermatology·S P BartonS Nicholls
Jan 1, 1980·The British Journal of Dermatology·C J Skerrow

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Citations

Jan 1, 1993·Archives of Dermatological Research·O MoriY Sasai
May 5, 2006·Journal of Intensive Care Medicine·Magda Cepkova, Michael A Matthay
Apr 1, 1983·The Journal of Dermatology·N KatoY Miura
Feb 22, 2002·The Journal of Surgical Research·Tor SvensjöElof Eriksson

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