PMID: 6107324Aug 1, 1980Paper

Changes in the adenohypophysis and genital tract of cryptorchid rats: some morphological and pharmacological aspects

The Journal of Endocrinology
O C PereiraH Hayashi

Abstract

It has been confirmed that cryptorchidism may affect the control mechanism of gonadotrophin secretion. This has been based on morphological aspects of the adenohypophysis of cryptorchid rats which have shown an increase in basophilic and vacuolated basophilic cells, an increase known to be related to the production of gonadotrophin. The morphological alterations observed in the testes, prostates, seminal vesicles and ductus deferentes of these cryptorchid animals, the quiescence and the responses of their seminal vesicles and ductus deferentes to sympathomimetic and parasympathomimetic drugs indicated that these cryptorchid animals may be somewhere between normal and castrated rats, although not equidistant from either. Comparison of wet weights and of occurrence of spontaneous contractions, and determination of drug parameters in seminal vesicles and ductus deferentes taken from normal, castrated or crptorchid rats, suggested that the development and the spontaneous or the pharmacological responses of male accessory organs of reproduction are independent phenomena.

Citations

May 17, 2005·Life Sciences·Oduvaldo Câmara Marques Pereira, Renata Carolina Piffer
May 29, 2003·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·O C M PereiraA C Arena
Oct 21, 1999·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·M S Souza, O C Pereira

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