PMID: 8467153Jan 1, 1993Paper

Changes in the blood endotoxin concentration after digestive surgery

Surgery Today
Y KokubaH Takagi

Abstract

Blood endotoxin concentrations measured in 57 patients with digestive disorders pre- and postoperatively, were found to peak one day after surgery, then gradually return to the preoperative level. The plasma endotoxin concentration was not significantly different in patients with and without liver cirrhosis before surgery, but was significantly higher in the cirrhosis group one day after surgery. The preoperative endotoxin concentration did not correlate with the white blood count (WBC), platelet count, or routine biochemical liver function tests, however, a significant negative correlation was observed between the plasma endotoxin and fibronectin concentrations. The ability of plasma to inactivate endotoxin was quantified by serial measurements of the endotoxin concentration following the addition of a known quantity to each patient's plasma. The plasma from normal subjects quickly inactivated endotoxin, but inactivation was decreased in the plasma from patients with liver failure.

Citations

Mar 29, 2005·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Guoxiang YaoZhuming Jiang
Jun 12, 2008·Langenbeck's Archives of Surgery·Klaus ButtenschoenDaniela Carli Buttenschoen
Mar 15, 2001·American Journal of Surgery·K ButtenschoenH G Beger
Mar 4, 2000·The Journal of Trauma·K ButtenschoenD C Buttenschoen
Sep 13, 2013·Critical Care : the Official Journal of the Critical Care Forum·Alexander KochKai Zacharowski
Nov 27, 2004·Clinica Chimica Acta; International Journal of Clinical Chemistry·Chieko Mitaka
May 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A NakaoH Takagi
Jan 1, 1997·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·A NakaoH Takagi
Apr 1, 1995·Clinical Microbiology Reviews·J C Hurley

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