Changes in the burden of malaria in sub-Saharan Africa

The Lancet Infectious Diseases
Wendy P O'MearaBrian Greenwood

Abstract

The burden of malaria in countries in sub-Saharan Africa has declined with scaling up of prevention, diagnosis, and treatment. To assess the contribution of specific malaria interventions and other general factors in bringing about these changes, we reviewed studies that have reported recent changes in the incidence or prevalence of malaria in sub-Saharan Africa. Malaria control in southern Africa (South Africa, Mozambique, and Swaziland) began in the 1980s and has shown substantial, lasting declines linked to scale-up of specific interventions. In The Horn of Africa, Ethiopia and Eritrea have also experienced substantial decreases in the burden of malaria linked to the introduction of malaria control measures. Substantial increases in funding for malaria control and the procurement and distribution of effective means for prevention and treatment are associated with falls in malaria burden. In central Africa, little progress has been documented, possibly because of publication bias. In some countries a decline in malaria incidence began several years before scale-up of malaria control. In other countries, the change from a failing drug (chloroquine) to a more effective drug (sulphadoxine plus pyrimethamine or an artemisinin com...Continue Reading

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Citations

Aug 21, 2013·Trends in Parasitology·Meera VenkatesanChristopher V Plowe
Feb 5, 2013·Lancet·Christopher DyeHiroki Nakatani
Apr 30, 2013·The Lancet Infectious Diseases·Cedric P YansouniMarleen Boelaert
Oct 20, 2011·The New England Journal of Medicine·UNKNOWN RTS,S Clinical Trials PartnershipPreeti Vansadia
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Jul 3, 2013·Malaria Journal·Sungano MharakurwaUNKNOWN Southern Africa ICEMR Team

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