PMID: 1194811Sep 1, 1975Paper

Changes in the concentration of calcitonin in the plasma of chick embryos during incubation

The Journal of Endocrinology
T G TaylorP E Lewis

Abstract

Calcitonin (CT) was assayed in the plasma of chick embryos at eight stages of development from day 17 of incubation to day 1 after hatching by a rat bioassay. The concentration of CT rose steadily from 1060 mu./1 on day 17 to 4700 mu./1 at the stage when pulmonary respiration was initiated on day 20. Nine hours later, when the embryos 'pipped' the shells, the concentration of the hormone more than doubled to reach a peak of 11000 mu./1. At hatching the level had fallen to 1400 mu./1 and 24 h later it was undetectable (less than 500 mu./1). The physiological significance of these changes is discussed in relation to the development of the embryo.

Citations

Feb 1, 1987·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·G C NicholsonT J Martin
Dec 1, 1985·The American Journal of Physiology·A MartzS G Langeluttig
Oct 1, 1982·Poultry Science·M P Richards

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