Changes in the institutional review board submission process for multicenter research over 6 years.

Nursing Outlook
Monika PogorzelskaElaine Larson

Abstract

Although collaborative research across sites is essential to increase the statistical power and generalizability of research findings, the need to undergo multiple institutional review board (IRB) reviews is a challenge. The purposes of this paper are to describe changes in the IRB submission process in 2 national multisite studies before and after the implementation of the Health Information Portability and Accountability Act (HIPAA) Privacy rule (2002 and 2008) and to discuss implications for policy and practice related to human subjects research. In the second study, there was a shorter mean approval time and reduced variability in the decision about the level of review, the mean number of pages per application doubled, and an increased proportion of IRBs required conflict of interest and data use agreements. Possible approaches to further enhance the efficiency and streamlining of the research review process are suggested.

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May 21, 2011·Cyberpsychology, Behavior and Social Networking·Brenda K Wiederhold
Feb 14, 2015·Clinical and Translational Science·Elaine L LarsonElizabeth G Cohn
Aug 5, 2014·American Journal of Obstetrics and Gynecology·Adi AbramoviciUNKNOWN National Perinatal Research Collaborative
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Apr 3, 2018·Clinical and Translational Medicine·Julie Babyar
Mar 23, 2017·Hospital Pharmacy·Marjorie Shaw PhillipsCraig Kirkwood
Jan 1, 2016·AJOB Empirical Bioethics·Daniel E HallRobert M Arnold

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