Changes in the internal structure of the human crystalline lens with diabetes mellitus type 1 and type 2

Ophthalmology
Nanouk G M WiemerBettine C P Polak

Abstract

To investigate the effect of diabetes mellitus (DM) type 1 and type 2 on the internal structure of the lens. Observational cross-sectional study. One hundred seven patients with DM type 1, 106 patients with DM type 2, and 75 healthy control subjects. Scheimpflug photography was used to image the lens of the right eye of 213 patients with DM and 75 healthy control subjects. The densitogram of the Scheimpflug image was used to indicate the nucleus and the different layers of the cortex of the lens. Lenses with cataract were excluded. The size of the nucleus and the different layers of the cortex of the lens. The nucleus and the different cortical layers of the DM type 1 lenses were significantly thicker compared with those of the control group (P<0.001). A significant association was found between the duration of DM type 1 and both the anterior and posterior cortex, its different layers, and the nucleus (P<0.001). The increase in the anterior and posterior cortex with the duration of DM was comparable with that of the nucleus. No important differences in the internal structure of the lens were found between the patients with DM type 2 and the control group. Diabetes mellitus type 1 has a significant effect on the internal structu...Continue Reading

References

Jul 1, 1992·The British Journal of Ophthalmology·J M SparrowH A Neil
Nov 1, 1990·The British Journal of Ophthalmology·J M SparrowH A Neil
Dec 1, 1986·International Ophthalmology·J M SparrowA R Hill
Jan 1, 1993·Eye·A J BronR Blakytny
Mar 1, 1993·The British Journal of Ophthalmology·Y SaitoM Okada
May 1, 1996·The British Journal of Ophthalmology·N LøgstrupA Green
Jul 11, 2001·Optometry and Vision Science : Official Publication of the American Academy of Optometry·M DubbelmanH A Weeber
Dec 2, 2004·Vision Research·M DubbelmanH A Weeber
Dec 16, 2005·The New England Journal of Medicine·Gijsbrecht J M TangelderPeter J Ringens
Jul 31, 2007·American Journal of Ophthalmology·Seang-Mei SawPaul J Foster

❮ Previous
Next ❯

Citations

Sep 11, 2012·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·William Neil Charman
Aug 16, 2014·Eye·A M Calvo-MarotoA Cerviño
Jun 8, 2015·Retina·Kata MiháltzPia Veronika Vecsei-Marlovits
Apr 3, 2009·Clinical & Experimental Ophthalmology·Alfred Wegener, Heike Laser-Junga
Oct 6, 2011·Experimental Eye Research·Aldo C Zamudio, Oscar A Candia
Mar 24, 2015·Biomedical Optics Express·X AdnanDavid A Atchison
Dec 6, 2016·Diabetic Medicine : a Journal of the British Diabetic Association·A KhanR A Malik
Mar 22, 2019·Journal of Ophthalmology·Ying XiaoHaidong Zou
Dec 10, 2009·Current Opinion in Ophthalmology

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.

Biomarkers for Type 2 Diabetes

Biomarkers can help understand chronic diseases and assist in risk prediction for prevention and early detection of diseases. Here is the latest research on biomarkers in type 2 diabetes, a disease in which the body is unable to produce or properly use insulin.

Related Papers

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Nanouk G M WiemerM Dubbelman
American Journal of Physiology. Cell Physiology
Rosana GeromettaOscar A Candia
© 2022 Meta ULC. All rights reserved