PMID: 7581546Feb 1, 1995Paper

Changes in the number of alpha 2- and beta-adrenoreceptors in the brain stem and cerebral cortex of rats in ontogeny

Fiziologicheskiĭ zhurnal imeni I.M. Sechenova
A A Iushkova, N N Dygalo

Abstract

Densities of alpha 2- and beta-adrenoceptors were higher in the brain stem of 21-day-old foetuses. The beta-receptors density, however, increased more rapidly in the brain stem after birth. The alpha 2-adrenergic receptors density gradually elevated with ageing in the cortex, the specifics of their ontogenesis being related to regulation of noradrenergic nerve cells function while that of the beta-adrenoceptors reflected a formation of adrenergic synapses in the brain areas in the course of development.

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