Changes in the structure and digestibility of myoglobin treated with sodium chloride.

Food Chemistry
Hui LiuChunbao Li

Abstract

Myoglobin is a protein not easily broken down by digestive enzymes due to its rigid structure. This study evaluated the structural characteristics of myoglobin under various sodium chloride treatments (0.4-0.8 mol/L for 5-10 h) and the impacts on its digestibility using spectroscopic and molecular dynamics simulation techniques. Myoglobin digestibility was 40% following pepsin digestion and 60% after being sequentially digested by pepsin and trypsin. The α-helix content of myoglobin did not change significantly following sodium chloride treatment but hydrophobic amino acids were exposed and the binding of phenylalanine targeted by some digestive enzymes became more stable, leading to the reduced digestibility.

References

Jan 1, 1991·Advances in Experimental Medicine and Biology·P KuzmicD H Rich
Mar 29, 2000·FEBS Letters·C MoczygembaP Wittung-Stafshede
Jun 26, 2002·Biochemistry·Gordon G Hammes
Aug 12, 2003·Proteins·Marcel L VerdonkRichard D Taylor
Aug 30, 2003·Science·Stephen J Benkovic, Sharon Hammes-Schiffer
Sep 14, 2004·Science·Ruhong ZhouBruce J Berne
Aug 4, 2006·The Journal of Physical Chemistry. B·Naoki Baden, Masahide Terazima
Mar 14, 2009·The Journal of Nutrition·Werner G Bergen, Guoyao Wu
Jul 23, 2009·Archives of Biochemistry and Biophysics·Enrica DroghettiGiulietta Smulevich
Nov 26, 2009·BMJ : British Medical Journal·Pasquale StrazzulloFrancesco P Cappuccio
Dec 29, 2009·Ecotoxicology and Environmental Safety·Nunu O MetreveliJoanna Skopinska
Nov 8, 2011·American Journal of Physiology. Heart and Circulatory Physiology·Mordecai P BlausteinW Gil Wier
Sep 1, 2006·Meat Science·Eoin Desmond
Mar 15, 2015·Food Chemistry·Yungang Cao, Youling L Xiong
Dec 7, 2016·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Amandeep KaurTarlok S Banipal
Mar 16, 2017·Food Research International·Li LiChunbao Li
Aug 16, 2017·International Journal of Biological Macromolecules·Khalida NasreenAsimul Islam
Jun 18, 2018·International Journal of Biological Macromolecules·Chunyi LiXiaolin Liu
Feb 21, 2019·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Mohd Shahnawaz KhanSadia Sumbul
Mar 20, 2019·Nature Protocols·André BrodkorbIsidra Recio
Jun 9, 2020·The Journal of Physical Chemistry. B·Shinya TaharaYasuhisa Mizutani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Biochemistry. Biokhimii︠a︡
A D Vinogradov
Medicina clínica
M Sabriá Leal
Nihon rinsho. Japanese journal of clinical medicine
Kenji Tokunaga, S Haraoka
Acta Medica Scandinavica. Supplementum
B SchersténG Jonsson
© 2021 Meta ULC. All rights reserved