Changes in the tumor marker concentration in female patients with hyper-, eu-, and hypothyroidism.

Endocrinologia Japonica
T Hashimoto, F Matsubara

Abstract

The levels of 6 circulating tumor markers were evaluated in a total of 131 female subjects with altered thyroid states; 36 normal subjects, 46 hyperthyroid patients with Graves' disease, and 49 primary hypothyroid patients. The mean CEA concentration was observed to be significantly higher (p less than 0.02) in hypothyroid patients than in normal and hyperthyroid patients (1.1 +/- 0.1 ng/ml, 0.8 +/- 0.1 ng/ml and 0.8 +/- 0.1 ng/ml, respectively). Similarly, the mean serum CA 125 concentration in hypothyroid patients was higher (p less than 0.02) than in normal and hyperthyroid patients (13.0 +/- 2.6 U/ml, 7.6 +/- 1.1 U/ml and 5.5 +/- 0.8 U/ml, respectively), and the mean serum CA 15-3 concentration in hypothyroid patients was significantly higher than in normal subjects (p less than 0.01) and hyperthyroid patients (p less than 0.001) (16.2 +/- 0.9 U/ml, 13.9 +/- 0.6 U/ml and 10.6 +/- 0.5 U/ml, respectively). No statistical difference was found in mean CA 19-9 in the three subject groups. AFP in the hypothyroid patients (3.6 +/- 0.3 ng/ml) was significantly higher (p less than 0.05) than in normal subjects (2.6 +/- 0.2 ng/ml) and hyperthyroid patients (1.7 +/- 0.2 ng/ml) (p less than 0.01). On the other hand, serum ferritin was ...Continue Reading

Citations

Jul 25, 2008·Thyroid : Official Journal of the American Thyroid Association·James C BartonUNKNOWN Hemochromatosis and Iron Overload Screening Study Research Investigators
Oct 26, 2002·BMJ : British Medical Journal·S T M KrishnanG Rayman
May 30, 2009·BMC Cancer·Jonathan L JesneckJoseph Y Lo
Sep 20, 2007·Endocrine Journal·Ryosuke KimuraTakashi Joh
Jul 21, 2007·Endocrine Journal·Hideo KaneharaNobuyoshi Tanaka
Jun 16, 2007·The American Journal of the Medical Sciences·Nobuyuki TakahashiYo Murakami
Feb 16, 2006·The American Journal of the Medical Sciences·Daniella R DuarteSergio A R Paiva
Jan 16, 2007·The American Journal of the Medical Sciences·Vidhya Subramanian, Subhashini Yaturu
Aug 27, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Andrea RavelliUNKNOWN Solid Tumor Working Party of European Blood and Marrow Transplantation Society (EBMT)
Mar 18, 2015·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Xiaomei YanQiu Yan
Jul 9, 2004·The Breast Journal·David Aguiar-BujandaJose Aguiar-Morales
Mar 17, 2005·Pediatric Blood & Cancer·Masahiro OgawaYoshihiro Komada
Aug 8, 2006·Thyroid : Official Journal of the American Thyroid Association·Henry VölzkeMarcus Dörr
May 2, 2018·Internal Medicine·Tomonori SekizakiHiroshi Nomoto
Mar 12, 2019·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·Inanc KarakoyunBanu Isbilen Basok
Jan 18, 2006·Clinical Chemistry·Michael J Duffy
Feb 1, 2020·International Journal of Pediatric Endocrinology·Jyotsna Gupta, Karen Lin-Su
Jul 1, 1994·Pathology·M ArumanayagamS R Swaminathan
Sep 8, 2010·Clinica Chimica Acta; International Journal of Clinical Chemistry·Michael J DuffyEnda W McDermott

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.