PMID: 6411172Aug 13, 1983Paper

Changes in volume and density of platelets in myocardial infarction

British Medical Journal
J F MartinY T Kishk

Abstract

The distributions of platelet volume and density were measured in 15 men suffering myocardial infarction and in 22 healthy controls. The method used separated 93% of the total platelet population from whole blood. Mean platelet volume of the study group compared with that of controls was increased by a mean of 0.98 fl (p less than 0.001) in the first 12 hours after myocardial infarction, and by 1.24 fl six weeks later (p less than 0.001). Distribution of platelet volume remained log normal after myocardial infarction. Modal platelet density was increased by a mean of 25 g/l (p less than 0.05) after myocardial infarction. Platelet volume is probably chronically large in men suffering myocardial infarction and may be related to changes in megakaryocytes. It is suggested that the increase in platelet volume occurs before infarction.

References

Sep 2, 1978·Lancet·F Angelico, P Amodeo
Apr 1, 1970·British Journal of Haematology·D G Penington, T E Olsen
Mar 1, 1968·The Journal of Clinical Investigation·L A Harker
May 3, 1980·Lancet·J R O'Brien
Jul 1, 1983·British Journal of Haematology·J F MartinD G Penington
Nov 15, 1982·Thrombosis Research·J F MartinD N Slater

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Citations

May 11, 2001·Clinical Cardiology·H SenaranS Kirazli
Jul 1, 1990·International Journal of Cell Cloning·A M Gladwin, J F Martin
Dec 1, 1988·Italian Journal of Neurological Sciences·E D'ErasmoG F Mazzuoli
Jan 24, 2007·Journal of Thrombosis and Thrombolysis·Atila BitigenNihal Ozdemir
Jan 18, 2003·Lipids·Yongsoon Park, William Harris
Jun 1, 1995·Pharmacology, Biochemistry, and Behavior·C OpperW Wesemann
Apr 18, 1992·Lancet·J F MartinM L Burr
Sep 19, 2012·Nature Reviews. Cardiology·John F MartinFizzah A Choudry
Jul 1, 1994·European Journal of Clinical Investigation·A BröijersénP Hjemdahl
Oct 1, 1992·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·M RøgerT Hovig
Sep 23, 2009·International Journal of Clinical Practice·L VizioliA Muscari
Jun 15, 1985·British Medical Journal·P C Milner, J F Martin
Jul 13, 1985·British Medical Journal·C B Thompson
Sep 1, 1986·Journal of Clinical Pathology·G K Sharma, I C Talbot
Feb 1, 1994·European Journal of Clinical Investigation·A S Brown, J F Martin
Aug 4, 2015·European Heart Journal·Bianca Rocca, Carlo Patrono
Aug 26, 2015·Indian Heart Journal·Musluhittin Emre Erkus, Recep Demirbag
Jun 6, 2009·Journal of Thrombosis and Haemostasis : JTH·S K BraekkanJ B Hansen
Aug 21, 2009·Journal of Thrombosis and Haemostasis : JTH·S G ChuJ S Berger
Feb 1, 1997·Baillière's Clinical Haematology·B van der Loo, J F Martin
Jun 1, 1993·Blood Reviews·S R Jackson, J M Carter
Sep 1, 1994·Baillière's Clinical Haematology·R E Smith, J F Martin
Jul 1, 1989·Baillière's Clinical Haematology·A EldorR F Levine
May 19, 1988·Diabetes Research and Clinical Practice·T J HendraJ S Yudkin
Jun 17, 2000·Baillière's Best Practice & Research. Clinical Haematology·J F MartinA Mathur
Aug 24, 2011·Scandinavian Journal of Clinical and Laboratory Investigation·Ebru TekbasMehmet S Ulgen

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