Changes of acid and alkaline phosphatase activities in the developing mouse brain

Biology of the Neonate
T B Ng, P P Tam

Abstract

Acid and alkaline phosphatase activities in the mouse cerebrum, brainstem and cerebellum increased during the late fetal and perinatal period and reached a maximum on postnatal day 28 (P28). Myelination was most extensive on P28-P45 in the brainstem and in the cerebellum, and phosphatidic acid phosphatase activity concomitantly decreased to a low level after birth. The changes in acid and alkaline phosphatase activities correlate more with the extent of myelination than with the overall brain tissue growth.

Citations

Aug 1, 1996·Lipids·M G Kocsis, R J Weselake
Dec 12, 2001·Cerebral Cortex·Caroline Fonta, Michel Imbert

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