PMID: 7087691Mar 1, 1982Paper

Changes of fatty acid composition of phospholipids in liver mitochondria and microsomes of the rat during growth

A KeränenM Hallman


The fatty acid patterns of rat liver mitochondrial and microsomal phospholipids were analyzed from term fetuses, 1 and 4 days old, and adult rats. The main fatty acids of phosphatidylethanolamine and -choline were stearic and palmitic acids, although the patterns differed slightly. The fatty acid composition of corresponding phospholipids in mitochondria and microsomes was similar. The fatty acid pattern of cardiolipin was dominated by linoleic acid. The most consistent feature of the developmental changes in the fatty acid patterns of all phospholipids studied was a decrease in the relative amount of monounsaturated fatty acids. The percentages of saturated fatty acids in phosphatidylethanolamine and -choline increased during neonatal development. It is suggested that the high levels of fetal monounsaturated fatty acids were due to low availability of polyunsaturated fatty acids.


Dec 7, 1966·Biochimica Et Biophysica Acta·J E Miller, W E Cornatzer
Mar 1, 1969·The Biochemical Journal·W C McMurray, R M Dawson
Jan 12, 1971·Biochimica Et Biophysica Acta·Y C AwasthiF L Crane
Jan 1, 1971·The Biochemical Journal·S JakovcicH Swift
Jan 1, 1973·Journal of Bioenergetics·T F Chuang, F L Crane
Jan 1, 1970·Biochimica Et Biophysica Acta·J G Parkes, W Thompson
Jan 19, 1973·Biochimica Et Biophysica Acta·M A Trewhella, F D Collins
Jan 1, 1973·Biology of the Neonate·J B Warshaw, R E Kimura
Jun 8, 1971·Biochimica Et Biophysica Acta·K Y HostetlerL L van Deenen
Dec 3, 1971·Biochimica Et Biophysica Acta·A ColbeauP M Vignais
Feb 1, 1970·European Journal of Biochemistry·F B Jungalwala, R M Dawson
Mar 19, 1971·Biochemical and Biophysical Research Communications·J B Davidson, N Z Stanacev
Apr 29, 1969·Biochimica Et Biophysica Acta·L M van GoldeL L van Deenen
Apr 1, 1962·The Biochemical Journal·G S GETZA RENSHAW
Oct 15, 1962·American Journal of Obstetrics and Gynecology·C M VAN DUYNEJ M FELTS

Related Concepts

Saturated Fat
Fetal Structures
Microsomes, Liver
Mitochondria, Liver

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