Changes of functional connectivity of the anterior cingulate cortex in women with primary dysmenorrhea

Brain Imaging and Behavior
Peng LiuWei Qin

Abstract

Primary dysmenorrhea (PDM), a common gynecological disorder, is associated with structural and functional alterations in several subregions of the anterior cingulate cortex (ACC). However, systematic functional connectivity of the ACC subregions in PDM has not been clarified. In this study, we used resting-state functional magnetic resonance imaging (fMRI) data from forty-eight PDM patients and thirty-eight matched female healthy controls to investigate the functional connectivity of ACC subregions in PDM. Compared to healthy controls, PDM patients exhibited increased connectivity between the caudal ACC (cACC) and primary somatosensory cortex (SI), between the perigenual ACC (pACC) and caudate, and between the subgenual ACC (sACC) and medial prefrontal cortex (mPFC). PDM patients also showed decreased connectivity between the pACC and precuneus. In PDM group, the connectivity of the right pACC-right caudate positively correlated with disease duration, and the connectivity of the left pACC-left precuneus negatively correlated with disease severity. These present findings reveal that abnormal ACC connectivity may be implicated in the PDM-related disturbances in pain sensory, modulation, and affection. We hope that our study could...Continue Reading

References

Sep 1, 1978·Journal of Behavioral Medicine·D J Cox, R G Meyer
Jun 1, 1979·British Journal of Obstetrics and Gynaecology·M AkerlundM L Forsling
Aug 1, 1987·Pain·Ronald Melzack
Dec 1, 1965·Archives of General Psychiatry·W W ZungM J Short
Nov 1, 1971·Psychosomatics·W W Zung
Dec 29, 2000·Neurophysiologie clinique = Clinical neurophysiology·R PeyronL García-Larrea
May 19, 2001·Journal of Pediatric and Adolescent Gynecology·A R Davis, C L Westhoff
Mar 4, 2003·Journal of Neurophysiology·Irina A StrigoM Catherine Bushnell
Nov 24, 2004·Trends in Cognitive Sciences·Matthew M BotvinickCameron S Carter
Jun 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·Michael D FoxMarcus E Raichle
Jul 5, 2005·Nature Reviews. Neuroscience·Brent A Vogt
Aug 27, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jon-Kar ZubietaChristian S Stohler
Sep 2, 2005·Nature Reviews. Neuroscience·Morten L Kringelbach
Mar 4, 2006·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Philippe A Chouinard, Tomás Paus
Mar 23, 2006·Nature Reviews. Neuroscience·David M Amodio, Chris D Frith
May 11, 2006·Japanese Journal of Clinical Oncology·Yuka Imamura, Hiroshi Sano
Aug 1, 2006·Health Care for Women International·Chung-Hey ChenKun-Ming Wu
Jul 3, 2007·NeuroImage·Daniel S MarguliesMichael P Milham
Nov 30, 2007·Pediatrics International : Official Journal of the Japan Pediatric Society·Murat CakirAysenur Okten
Jan 30, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Matthias BeckmannMatthew F S Rushworth
Feb 4, 2009·Proceedings of the National Academy of Sciences of the United States of America·C J HoneyP Hagmann
May 28, 2010·Arthritis and Rheumatism·Vitaly NapadowRichard E Harris
Aug 14, 2010·Pain·Cheng-Hao TuJen-Chuen Hsieh
May 20, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·David A SeminowiczLaura S Stone
Jul 2, 2011·Anesthesiology·Ajay D WasanRandy L Gollub
Oct 1, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marwan N BalikiA Vania Apkarian
Apr 27, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P LiuJ Tian
Jan 17, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Amanda V UtevskyScott A Huettel
Apr 20, 2016·Scientific Reports·Ting-Hsuan WuJen-Chuen Hsieh
Oct 16, 2016·Brain Imaging and Behavior·Peng LiuWei Qin

❮ Previous
Next ❯

Citations

Aug 12, 2018·European Journal of Pain : EJP·Bettina BöttcherSigrid Elsenbruch
Dec 14, 2018·Frontiers in Neuroscience·Intan LowLi-Fen Chen
Sep 10, 2019·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Rodrigo PegadoGrasiéla Nascimento Correia
Jul 28, 2021·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Siyi YuJie Yang

❮ Previous
Next ❯

Methods Mentioned

BETA
structural magnetic resonance

Related Concepts

Related Feeds

Brain Imaging of Neural Circuits

Neural circuits are groups of interconnected neurons which carry out specific functions when activated. Imaging these neural circuits allows researches to further elucidate their mechanisms and functions. Follow this feed to stay up to date on brain imaging of neural circuits.

Brain Imaging of Neural Circuits (MDS)

Neural circuits are groups of interconnected neurons which carry out specific functions when activated. Imaging these neural circuits allows researches to further elucidate their mechanisms and functions. Follow this feed to stay up to date on brain imaging of neural circuits.

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.