PMID: 7024440Aug 1, 1981Paper

Changes of hypothalamic LH-RH content induced by estradiol injection into female rats (author's transl)

Nihon Sanka Fujinka Gakkai zasshi
A Saito

Abstract

The 4 day cycling Wistar strain rats were sacrificed by decapitation on the several conditions. By radioimmunoassay, hypothalamic luteinizing hormone-releasing hormone (LH-RH) and serum luteinizing hormone (LH) were measured. From the present experiments, the following results were obtained. 1. At 17:00 on proestrus, a peak in serum LH level was observed. At the same time, hypothalamic LH-RH content was decreased. 2. After the administration of estradiol (E2) on diestrus I, hypothalamic LH-RH content increased gradually and reached the peak about one day later. Moreover, serum LH peak appeared on diestrus II. But the change of E2 administration time didn't take part in the time of LH peak. 3. When the group of the rats were administered progesterone at appropriated time in addition to the E2 administration at 12:00 on diestrus I, serum LH peak on diestrus II was repressed through the changes of LH-RH.

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.