Changes of NK cells in preeclampsia

American Journal of Reproductive Immunology : AJRI
Atsushi FukuiHideki Mizunuma

Abstract

The regulation of uterine and circulating peripheral blood natural killer (NK) cells has been associated with reproductive immunology such as recurrent pregnancy losses, implantation failures, or preeclampsia. Preeclampsia is a hypertensive disorder of pregnancy characterized by increased blood pressure accompanied by proteinuria and is a major cause of maternal and fetal mortality. Natural cytotoxicity receptors (NCRs) are unique markers, which regulate NK cell cytotoxicity and cytokine production. The relation of NCRs to reproduction is not fully characterized yet. The different profile of NCRs expression may suggest presence of abnormal regulation of NK cell in women with reproductive failures. Pregnant women with preeclampsia carry immunological abnormalities of NCRs on peripheral blood NK cells during pregnancy. The lower expression of NKp46(+) NK cells in women with preeclampsia may account for the higher production of NK1 cytokine that is known as NK1 shift in pregnant women with preeclampsia. Evaluation of NKp46 on peripheral blood NK cells may be applicable to find the onset of preeclampsia. In this review, various expressions of NK cell surface markers including NCRs on NK cells, NK cell cytotoxicity, and production o...Continue Reading

References

Jul 7, 1999·American Journal of Reproductive Immunology : AJRI·A FukuiY Saito
Aug 5, 2000·Journal of Reproductive Immunology·S Saito
Sep 6, 2001·European Journal of Immunology·T I ArnonO Mandelboim
Sep 5, 2002·Nature Reviews. Immunology·Ashley Moffett-King
Feb 28, 2003·American Journal of Reproductive Immunology : AJRI·Dorota Darmochwal-KolarzJan Oleszczuk
Aug 5, 2003·Journal of Reproductive Immunology·Shigeru Saito, Masatoshi Sakai
Feb 3, 2004·Journal of Cellular and Molecular Medicine·R BiassoniN Dimasi
Oct 13, 2004·The Journal of Experimental Medicine·Susan E HibyAshley Moffett
Nov 27, 2004·BMJ : British Medical Journal·Ashley MoffettPeter Braude
Apr 6, 2005·The Journal of Experimental Medicine·Sumati Rajagopalan, Eric O Long
Oct 8, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Pietro ForteJörg D Seebach
Mar 4, 2006·Reproduction : the Official Journal of the Society for the Study of Fertility·A BhallaL W Chamley
Apr 4, 2006·Lancet·Khalid S KhanPaul Fa Van Look
Apr 22, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ori NevoIsabella Caniggia
Sep 8, 2006·The New England Journal of Medicine·Richard J LevineUNKNOWN CPEP Study Group
Apr 17, 2007·Molecular Aspects of Medicine·Shigeru SaitoYasushi Sasaki
Apr 20, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sarah J GermainChristopher W Redman
May 8, 2007·Journal of Reproductive Immunology·I L SargentC W G Redman
Sep 11, 2007·American Journal of Obstetrics and Gynecology·Tiffany A Moore SimasSharon E Maynard
Nov 2, 2007·The Journal of Investigative Dermatology·Emanuela CagnanoAngel Porgador
Apr 15, 2008·American Journal of Reproductive Immunology : AJRI·Satyan KalkunteSurendra Sharma
Jul 22, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Irit ManasterOfer Mandelboim
Feb 10, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Gili G HalfteckOfer Mandelboim
Mar 11, 2009·Hypertension·Leona C Y PoonKypros H Nicolaides
Mar 21, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Satyan S KalkunteSurendra Sharma
Apr 8, 2009·The Journal of Clinical Investigation·Tadepally LakshmikanthFrancesco Colucci
Aug 22, 2009·American Journal of Reproductive Immunology : AJRI·Nora BachmayerEva Sverremark-Ekström
Jan 13, 2010·American Journal of Reproductive Immunology : AJRI·Dong Wook ParkKwang Moon Yang
Mar 25, 2010·American Journal of Reproductive Immunology : AJRI·Christopher W G Redman, Ian L Sargent
May 12, 2010·American Journal of Reproductive Immunology : AJRI·Shigeru SaitoMika Ito
Sep 10, 2010·American Journal of Reproductive Immunology : AJRI·Hyunkyong AhnJoanne Kwak-Kim
Sep 14, 2010·American Journal of Obstetrics and Gynecology·Attila MolvarecShigeru Saito

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Citations

Apr 9, 2013·Cellular & Molecular Immunology·Haoyu SunWeihua Xiao
Jun 24, 2014·Cellular & Molecular Immunology·Ester Leno-DuránIrene Tirado-González
Jul 3, 2013·Physiology·Babbette LaMarcaKedra Wallace
Sep 24, 2015·Scientific Reports·Bart GroenMarijke M Faas
Jan 26, 2018·Journal of Cardiovascular Development and Disease·Gonçalo Miguel PeresElisa Cairrão
Dec 10, 2017·Clinical Science·Erin B Taylor, Jennifer M Sasser
Jan 5, 2019·Reproductive Sciences·S Joseph HuangCharles J Lockwood
Feb 28, 2019·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Venkata Ramana VakaBabbette LaMarca
Feb 11, 2019·Scandinavian Journal of Immunology·Hui-Qing Lu, Rong Hu
Sep 9, 2020·American Journal of Reproductive Immunology : AJRI·Atsushi FukuiHiroaki Shibahara
May 28, 2019·Frontiers in Immunology·Nanna JørgensenThomas Vauvert F Hviid
May 3, 2018·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Corbin A ShieldsDenise C Cornelius
Aug 7, 2018·Frontiers in Immunology·Janri GeldenhuysMarleen Magdalena Kock
Apr 23, 2020·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Olivia K TravisDenise C Cornelius
Feb 16, 2017·American Journal of Hypertension·Catalina A Lopez Gelston, Brett M Mitchell
Oct 19, 2017·Clinical Science·Jamil ElfarraDenise C Cornelius
Dec 15, 2020·American Journal of Reproductive Immunology : AJRI·Olivia K TravisDenise C Cornelius
Nov 22, 2020·International Journal of Molecular Sciences·Loredana AlboniciRoberto Bei
Dec 18, 2020·Frontiers in Immunology·João MendesAnabela Mota-Pinto
Mar 27, 2021·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Gustav van NiekerkAnna-Mart Engelbrecht
Feb 4, 2021·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Jesse N CottrellLorena M Amaral
Jun 19, 2021·Communications Biology·Sophie BergmannThorsten E Boroviak
Jun 3, 2021·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Olivia K TravisDenise C Cornelius
Aug 25, 2021·Cellular & Molecular Immunology·Fuyan WangFrancesco Colucci

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